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Stable isotope applications to monitor starch digestion and fermentation for the development of functional foods.

Objective

The aim of this project is to characterise the "metabolic quality" of carbohydrates, with the main focus on starch. With 13C-stable isotope techniques, 13C-glucose response to various 13C-starch sources will be studied, including functions that could modulate this response such as gastric emptying / intestinal transit time and digestion rates. These functions will be manipulated by addition of rat, protein, dietary fibre and enzyme inhibitors in order to optimise the glycemic response. Fermentation of 13C-starch in man will be characterised by measuring small intestinal bioavailability, 13C-short chain fatty acid production and bacterial flora. This project will lead to a rationale for the development of breakfast food / biscuits with the target groups healthy people, diabetic patients and people at risk to diabetes and obesity.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

LUND UNIVERSITY
Address
60,Getingevaegen 60
221 00 Lund
Sweden

Participants (5)

CENTRE DE RECHERCHE EN NUTRITION HUMAINE DE LYON
France
Address
Place D'arsonval
69437 Lyon
GROUPE DANONE
France
Address
7,Rue De Tthtran 7
75381 Paris
HUMAN NUTRITION RESEARCH CENTRE OF NANTES
France
Address
Allee De L'ile Gloriette 5, Hotel Dieu
44093 Nantes
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
Address
Herestraat 49
3000 Louvain / Leuven
UNIVERSITY OF GLASGOW
United Kingdom
Address
Rankine Avenue
G75 0QF Glasgow