Objective Monogenetic synthetic peptides from the two animal viruses canine provirus and bovine respiratory syncytial virus will be applied as vaccines in the form of lipopeptides. These will be constructed in several different ways including the synthesis of palmitoyl-thioesters and by combinatorial chemistry with the basis in Pam3Cys constructs. Adjuvants and vehicle systems based on quillaja saponins of defined structure converted to ISCOMs will be used as vehicle/adjuvant system for enhanced presentation of the peptides. The lipopeptides will be analysed in great detail by means of advanced analytical technique. Animal experiments including a challenge experiment in target animal. Fields of science natural sciencesbiological sciencesmicrobiologyvirologynatural sciencesbiological sciencesbiochemistrybiomoleculesmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-2. - Key action Control of Infectious Diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator UNIVERSITY OF COPENHAGEN Address 3 c,blegdamsvej 3 c 2200 Koepenhagen Denmark See on map EU contribution € 0,00 Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all PEPSCAN SYSTEMS B.V. Netherlands EU contribution € 0,00 Address Edelhertweg 15 8203 AB Lelystad See on map
