Objective
The goal of this work is to optimise an in vitro system:
i) for testing anti-viral compounds that exclusively reduce translation from viral IRES containing mRNAs and;
ii) for rational design of mutations reducing efficiency of viral translation for the development of attenuated vaccine.
Fields of science
- medical and health scienceshealth sciencesinfectious diseasesRNA viruses
- natural sciencesbiological sciencesmicrobiologyvirology
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines
- natural sciencesbiological sciencesgeneticsmutation
- natural sciencesbiological sciencesgeneticsRNA
Call for proposal
Data not availableFunding Scheme
RGI - Research grants (individual fellowships)Coordinator
EUROPEAN MOLECULAR BIOLOGY LABORATORY
EU contribution
No data
Address
Meyerhofstrasse 1
HEIDELBERG
Germany
HEIDELBERG
Germany
Total cost
No data