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Development of a new in vitro test for drugs and vaccine design against plus-stranded rna viruses containig ires elements

Objectif

The goal of this work is to optimise an in vitro system:
i) for testing anti-viral compounds that exclusively reduce translation from viral IRES containing mRNAs and;
ii) for rational design of mutations reducing efficiency of viral translation for the development of attenuated vaccine.

Appel à propositions

Data not available

Coordinateur

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Contribution de l’UE
Aucune donnée
Adresse
Meyerhofstrasse 1
HEIDELBERG
Allemagne

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Coût total
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