Objectif
The goal of this work is to optimise an in vitro system:
i) for testing anti-viral compounds that exclusively reduce translation from viral IRES containing mRNAs and;
ii) for rational design of mutations reducing efficiency of viral translation for the development of attenuated vaccine.
Champ scientifique
- medical and health scienceshealth sciencesinfectious diseasesRNA viruses
- natural sciencesbiological sciencesmicrobiologyvirology
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines
- natural sciencesbiological sciencesgeneticsmutation
- natural sciencesbiological sciencesgeneticsRNA
Appel à propositions
Data not availableRégime de financement
RGI - Research grants (individual fellowships)Coordinateur
HEIDELBERG
Allemagne