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Content archived on 2024-05-27

Paediatric european network for treatment aids

Objective

The primary aim of PENTA is to evaluate new antiretroviral and immune therapies in children, and particularly to develop trials addressing important management issues, which cannot be assumed from results of trials in adults. Has established a network of paediatric centres and collaborating laboratories from 11 European countries to undertakemulticentre clinical trials. With the prolongation of disease-free life associated with potent antiretroviral therapy(ART), new therapies are evaluated in adult trials using endpoints of viral load reduction and immune response. However, there are important differences between adults and children in these parameters. Pharmacokinetic studies are essential as some drugs such as the protease inhibitors are metabolised faster in children and extrapolating from adult data would result in under dosing which could increase the risk of developing resistance to HIV. Increased collaboration with other international groups running studies in HIV infected children is planned for new trials and for undertaking meta-analyses. Collaboration and communication between clinical centres will be increased through pentad newsletter, training exchanges and the development of a PENTA website.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CON - Coordination of research actions

Coordinator

AZIENDA OSPEDALIERA DI PADOVA
EU contribution
No data
Address
via Giustiniani 3
35128 PADOVA
Italy

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (91)

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