Objective Microbial drug resistance imposes an increasing threat to human and animal health and the development of new drugs to control bacterial infections is therefore urgently needed. The overall objective of this project is to exploit a new class of bacterial targets called two-component systems (TCS) for the development of novel antibacterial and drugs that specifically target the mechanisms by which bacteria establish infection in the host. This objective will be achieved by targeting pan-European critical mass, expertise and support to understanding of the structure, function and biological diversity of these targets. By the end of the project we will expect to have selected appropriate targets and have developed selective assays for inhibitors of those targets that can be used for high throughput screening in the pharmaceutical industry. Fields of science natural sciencesbiological sciencesmicrobiologybacteriologymedical and health sciencesbasic medicinepharmacology and pharmacydrug resistance Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-2. - Key action Control of Infectious Diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator INSTITUTE OF FOOD RESEARCH EU contribution No data Address Norwich Research Park, Colney NORWICH United Kingdom See on map Links Website Opens in new window Total cost No data Participants (5) Sort alphabetically Sort by EU Contribution Expand all Collapse all CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE France EU contribution No data Address Route de Narbonne 118 Univ. P.Sabatier Toulouse 3 31062 Toulouse See on map Total cost No data CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Spain EU contribution No data Address 144,Velazquez 144 28006 MADRID See on map Total cost No data UNIVERSITE PAUL SABATIER DE TOULOUSE III France EU contribution No data Address Route de Narbonne 118 31062 TOULOUSE See on map Total cost No data UNIVERSITY OF GLASGOW United Kingdom EU contribution No data Address University Avenue GLASGOW See on map Total cost No data UNIVERSITÀ DEGLI STUDI DI SIENA Italy EU contribution No data Address Viale Bracci Policlinico dellle Scotte 53100 SIENA See on map Total cost No data
