The co-operation of subunits in polyketide synthases

Project Information

PETRA ZIEGLER

Grant agreement ID: QLK2-CT-2000-51154

Project closed

Start date 15 January 2001

End date 14 July 2002

Funded under

• Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Total cost € 85 704,00

EU contribution € 85 704,00

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

Objective

Truncated versions of the erythromycin-producing polyketide synthase (PKS) will be engineered, in which specific active sites are mutated. The pattern of intersubunit protein-protein interaction in these giant multienzymes will be deduced by studying heterodimers of such mutants.

Fields of science

• natural sciences › biological sciences › biochemistry › biomolecules › proteins › proteomics

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-2. - Key action Control of Infectious Diseases

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

• EU contribution: No data
• Address: Hills Road Addenbrooke's Hospital ; CB2 2QR Cambridge ; United Kingdom
• Total cost: No data