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Content archived on 2024-05-24

The co-operation of subunits in polyketide synthases

Objective

Truncated versions of the erythromycin-producing polyketide synthase (PKS) will be engineered, in which specific active sites are mutated. The pattern of intersubunit protein-protein interaction in these giant multienzymes will be deduced by studying heterodimers of such mutants.

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Call for proposal

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Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
EU contribution
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Address
Hills Road Addenbrooke's Hospital
CB2 2QR Cambridge
United Kingdom

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