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Content archived on 2024-05-27

Identification of efficacious delivery systems for recombinant and nucleic acid construct vaccines (EFFICACIOUS DELIVERY)

Objective

Classical swine fever virus (CSFV) is a well-suited model for the evaluation of protective immunity in swine induced by virus subunits. Novel vaccines, which are investigated in this project, can be divided into two groups, 1. Viral subunit antigens generated in vitro and 2. DNA- or RNA-based delivery systems and a Para poxvirus-based expression system, producing the relevant antigens in vivo. In addition the modification of such vaccines with potent immuno-modulatorymolecules and loading of dendrite cells (DC) will be tested for improving stimulatory-stimulatory effects in swine. Since only highly efficacious vaccines are responsible for a rapid onset of protection in naive animal populations this study will focus on the immune response after primary vaccination. The results of the study will provide sufficient information to be able to identify efficient vaccine-types against CSFV as well as other emerging diseases.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

FRIEDRICH-LOEFLER INSTITUTE FEDERAL RESEARCH INSTITUT FOR ANIMAL HEALTH
EU contribution
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Address
Paul Ehrlichstr. 28
72076 TUEBINGEN
Germany

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (6)

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