Objective Bluetongue virus (BTV) has a track record of incursion into the EU & causing severe disease & financial losses to our livestock industry. However, the EU has no coherent vaccination policy, which makes BTV incursions difficult or impossible to control. This project will enable an effective policy to be established for the first time by testing the existing live virus vaccines for efficacy & safety, & by providing clear science-based recommendations on their use or otherwise in Europe. The project will also seek to develop & produce inactivated vaccines conferring enhanced protection using state of the art technology with engineered "virus-like particles" & slow release delivery systems. In addition, by sequencing live vaccine strains of BTV & wild strains isolated in the field around Europe, database will be established to enable sourcing of European BTV incursions & early detection of vaccine breakdown thus facilitating targeting of control measures. Fields of science natural sciencescomputer and information sciencesdatabasesnatural sciencesbiological sciencesmicrobiologyvirologymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccinesagricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandry Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-2. - Key action Control of Infectious Diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator INSTITUTE FOR ANIMAL HEALTH Address Ash road, nr woking GU24 0NF Woking United Kingdom See on map EU contribution No data Participants (4) Sort alphabetically Sort by EU Contribution Expand all Collapse all AGRICULTURAL RESEARCH COUNCIL South Africa EU contribution € 0,00 Address X055,old soutpan road, private bag x5 0110 Pretoria See on map Other funding No data LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE United Kingdom EU contribution € 0,00 Address Keppel street WC1E 7HT London See on map Other funding No data MERIAL LIMITED United Kingdom EU contribution € 0,00 Address Kinghtsbridge 27 SW1 7QT London See on map Other funding No data THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON United Kingdom EU contribution € 0,00 Address Brunswick square 29-39 WC1N 1AX London See on map Other funding No data