Type 1 diabetes is a common chronic disease mainly arising in children and young people. In Europe, its incidence is high and steadily increasing. The disease is caused by the destruction of insulin-producing cells in the pancreas. Many studies have suggested that enterovirus infections can induce this process. Recently, substantial new evidence has been obtained further supporting their role. This study aims to confirm the link between enterovirus infections and Type 1diabetes in five EU countries and characterize the molecular determinants, which make these viruses diabetogenic. The final goal is to find out if Type 1 diabetes can be prevented by an enterovirus vaccine and provide information needed for the development of such vaccines.
Funding SchemeCSC - Cost-sharing contracts
SE1 7EH London
581 85 Linkoeping
E1 2BB London