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Enterovirus infections as a risk factor for type 1 diabetes

Objective

Type 1 diabetes is a common chronic disease mainly arising in children and young people. In Europe, its incidence is high and steadily increasing. The disease is caused by the destruction of insulin-producing cells in the pancreas. Many studies have suggested that enterovirus infections can induce this process. Recently, substantial new evidence has been obtained further supporting their role. This study aims to confirm the link between enterovirus infections and Type 1diabetes in five EU countries and characterize the molecular determinants, which make these viruses diabetogenic. The final goal is to find out if Type 1 diabetes can be prevented by an enterovirus vaccine and provide information needed for the development of such vaccines.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

UNIVERSITY OF TAMPERE
Address
4,Medisiinarinkatu 3
33014 Tampere
Finland

Participants (6)

CENTRE HOSPITALIER RGIONAL ET UNIVERSITAIRE DE LILLE
France
Address
Place De Verdun 1
59037 Lille
KING'S COLLEGE LONDON
United Kingdom
Address
Lambeth Palace Road
SE1 7EH London
LINKOEPING UNIVERSITY
Sweden
Address

581 85 Linkoeping
NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS
Greece
Address
Phidippidou Street 55
11527 Athens
QUEEN MARY AND WESTFIELD COLLEGE - UNIVERSITY OF LONDON
United Kingdom
Address
Whitechapel Rd
E1 2BB London
UNIVERSITY OF ESSEX
United Kingdom
Address
Wivenhoe Park John Tabor Laboratories
CO4 3SQ Colchester