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Creutzfeldt-Jakob disease: epidemiology, risk factors, diagnostic tests and genetics

Objective

There is compelling evidence that the same agent is responsible for variant CJD (vCJD) and bovine spongiform encephalopathy. Cases of vCJD have been identified in the UK, France and the Republic of Ireland. It is not possible to predict the numbers of cases that may occur in European countries. It is essential to monitor this disease and to identify relevant risk factors for vCJD. In order to achieve this, it is necessary to identify all forms of CJD, including atypical phenotypes of sporadic CJD (sCJD). Prion protein (PrP) genotype is an important determinant of disease susceptibility and phenotype. Detailed population studies of PrP genotype are necessary in order to address issues of age and gender distributions of CJD within a given region and issues of differing incidence between regions. This proposal addresses these objectives through the co-ordination and harmonization.

Call for proposal

Data not available

Coordinator

STATENS SERUM INSTITUT
Address
5,Artillerivej 5
2300 Koepenhagen
Denmark
 

Participants (11)

BARJIIAL MEDICAL CENTRE
Israel
Address
Barjiial Medical Centre
78305 Ashkaion
 
BEAUMONT HOSPITAL
Ireland
Address
Beaumont Road
9 Dublin
 
ERASMUS UNIVERSITEIT ROTTERDAM
Netherlands
Address
50,Dr. Molewaterplein 50
3015 GE Rotterdam
 
NATIONAL PUBLIC HEALTH INSTITUTE
Finland
Address
Mannerheimintie 16
00300 Helsinki
 
NORWEGIAN INSTITUTE OF PUBLIC HEALTH
Norway
Address
75,Geitmyrsveien 75 Torshov
0403 Oslo
 
SCIENTIFIC INSTITUTE OF PUBLIC HEALTH
Belgium
Address
Rue Juliette Wytsman 14
1050 Bruxelles
 
SMITTSKYDDSINSTITUTET
Sweden
Address

17182 Solna
 
UNIVERSIDADE DE LISBOA
Portugal
Address
Av. Prof. Egas Moniz
1649 035 Lisboa
 
UNIVERSITAIRE INSTELLING ANTWERPEN - UNIVERSITEIT ANTWERPEN
Belgium
Address
Universiteitsplein 1
2610 Wilrijk (Antwerpen)
 
UNIVERSITY OF HELSINKI
Finland
Address
Haartmaninkatu 3
00014 Helsinki
 
UNIVERSITY OF ICELAND
Iceland
Address
Keldur V/vesturlandsveg
112 Reykjavik