Intermodular transfer in antibiotic mixed polyketide-peptide synthetases

Project Information

JOSE GARCIA-BERNARDO

Grant agreement ID: QLK2-CT-2001-52159

Project closed

Start date 1 January 2002

End date 31 December 2003

Funded under

• Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Total cost € 114 272,00

EU contribution € 114 272,00

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

Objective

Polypeptides and non-ribosomal encoded polypeptides are a rich natural source of antibiotics. Hybrid multienzymes will be engineered containing modules drawn from both PKS and NRPS, and the products characterised. It is aimed both to uncover the rules for productive linking of PKS and NRPS modules and to apply these rules to produce novel and potentially useful peptide-polypeptides.

Fields of science

• medical and health sciences › basic medicine › pharmacology and pharmacy › pharmaceutical drugs › antibiotics

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-2. - Key action Control of Infectious Diseases

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

• EU contribution: No data
• Address: 80,Tennis Court Road, 80 ; CB2 1GA CAMBRIDGE ; United Kingdom
• Total cost: No data