Objective Drug resistance arises in Mycobacterium tuberculosis (MTB) generally by mutation of chromosomal genes, but despite combined drug therapy the spread of multi-drug- resistant (MDR) strains is alarmingly increasing. The LONG-DRUG project is a longitudinal study, carried out in prisons and the civil society in an area with high MDR-TB prevalence, which aims to document the generation of multi drug resistant MTB strains through the use of novel molecular techniques. The combined use of a variety of techniques on longitudinally obtained samples and primary cultures will enable to generate clinically significant knowledge on the evolution of multi drug resistance in Mycobacterium. Fields of science medical and health sciencesclinical medicinepneumologytuberculosisnatural sciencesbiological sciencesgeneticsmutationsocial sciencespolitical sciencespolitical policiescivil societymedical and health sciencesbasic medicinepharmacology and pharmacydrug resistancemultidrug resistance Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-2. - Key action Control of Infectious Diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator UNIVERSIT DEGLI STUDI DI SIENA EU contribution No data Address Via Bracci, 16 53100 SIENA Italy See on map Total cost No data Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all EPICENTRE - GROUPE EUROPEEN D'EXPERTISE EN EPIDEMIOLOGIE D'INTERVENTION France EU contribution No data Address 8,Rue Saint Sabin 8 75011 PARIS See on map Total cost No data ESSAI CLINIQUE EVALUATION EPIDEMIOLOGIE STATISTIQUES France EU contribution No data Address Rue A Lancon, 49 75013 PARIS See on map Total cost No data FONDATION MEDECINS SANS FRONTIERES France EU contribution No data Address rue Saint Sabin 8 75011 PARIS See on map Total cost No data ISTITUTO SUPERIORE DI SANITA Italy EU contribution No data Address Viale Regina Elena 299 00161 ROMA See on map Total cost No data LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH Germany EU contribution No data Address 5,Leopoldstrasse 5 80802 MUENCHEN See on map Total cost No data RESEARCH CENTER BORSTEL, CENTER FOR MEDICINE AND BIOLOGICAL SCIENCE Germany EU contribution No data Address 18,Parkallee 18 23845 BORSTEL See on map Total cost No data UNIVERSITY OF CAGLIARI Italy EU contribution No data Address Via Binaghi, 4 09121 CAGLIARI See on map Total cost No data UNIVERSITY OF LEICESTER United Kingdom EU contribution No data Address Maurice Shock Building LE1 9HN LEICESTER See on map Total cost No data