Modulation of kynurenic acid synthesis in rodent models of retinal degeneration

Objective

Gynogenic acid (KYNA) may act as a neuroprotectant against retinal degeneration. I will investigate modulation of its retinal content and the expression and cellular distribution of key enzymes of KYNA synthesis kynurenine ammotransferases I and II (KAT I and II) in rodent models of optic nerve trauma, glaucoma and diabetic retinopathy

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-2. - Key action Control of Infectious Diseases

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

THE UNIVERSITY OF TUEBINGEN

Address

Roentgenweg, 11
72076 Tuebingen
Germany