Objective
The aim is to identify and exploit viral modifiers of apoptosis and cytokine responses (particularly Toners) as a potential source of novel health care pharmaceuticals for manipulation of immune responses and treatment of certain diseases. Such virus genes will be identified by nucleotide sequence and functional analysis of cloned viral Orbs and coda libraries of three large DNA viruses (African swine fever, Extremely and Mouse herpes). Possible human homologue of novel sequences will be characterised. The cellular targets of these viral evasion genes and their impact on apoptosis and virus pathogenesis will be determined. Determination of minimal active sequences will permit the development of low molecular weight peptide drugs, starting with the calcineurin phosphates inhibitor A238L gene of ASFV.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs
- natural sciences biological sciences microbiology virology
- medical and health sciences basic medicine immunology
- natural sciences mathematics pure mathematics mathematical analysis functional analysis
- medical and health sciences health sciences infectious diseases DNA viruses
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
2780-156 OEIRAS
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.