Objective The objective is to develop and demonstrate a new gene array technology platform for high-throughput diagnosis of CF and CF-related diseases as a model for other genetic diseases. An integrated magnetic sensor-based gene array will be developed comprising novel giant magneto resistance or tunnel magneto resistance sensors for direct magnetic detection of hybridisation of target DNA-tagged magnetic beads. New CF diagnostic assays will be developed based on oligonucleotide or based-based magnetic sensor array detection of qualitative or quantitative changes in RNA products resulting from either mutations in the CFTR gene (splice site mutations) or possible atypical RNA expression patterns from other genes caused by the presence of an abnormal CFTR gene. Screens for known mutations in the CFTR gene caused by Snips in genomic DNA samples from blood using a novel primer-extension based micro array method will also be developed Fields of science natural sciencesbiological sciencesgeneticsDNAnatural sciencesbiological sciencesgeneticsmutationengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsnatural sciencesbiological sciencesgeneticsRNA Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-3. - Key action The "Cell factory" Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator National Microelectronics Research Center Address Prospect row, lee malting 30 Ireland See on map EU contribution No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all FUNDAÇAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA Portugal EU contribution € 0,00 Address Campo grande c8 1749-016 Lisboa See on map Other funding No data INSTITUTO DE ENGENHARIA DE SISTEMAS E COMPUTADORES Portugal EU contribution € 0,00 Address Rua alves redol 9 1000 Lisboa See on map Other funding No data INTERUNIVERSITAIR MIKRO-ELEKTRONICA CENTRUM VZW Belgium EU contribution € 0,00 Address 75,kapeldreef 75 3001 Heverlee See on map Other funding No data MWG-BIOTECH UK LTD United Kingdom EU contribution € 0,00 Address Mill court, featherstone road, wolverton mill sout MK12 5RD Milton keynes See on map Other funding No data NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS Greece EU contribution € 0,00 Address Thivon and levadias str., st sofia's children hosp 11527 Athens See on map Other funding No data NATIONAL UNIVERSITY OF IRELAND DUBLIN Ireland EU contribution € 0,00 Address Our lady's hospital for sick children, crumlin 12 Dublin See on map Other funding No data UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK Ireland EU contribution € 0,00 Address Western road Cork See on map Other funding No data
