Early diagnosis of Alzheimer's disease and related dementia

Objective

Alzheimer's disease (AD) and related dementia are irreversible, degenerative disorders of the brain characterised by progressive cognitive decline, the loss of personality and finally death. Because of the impact on individuals and due to the enormous costs for health care and thus for society, these disorders present a major health problem to the EU. Treatment that can prevent, arrest and reverse degeneration and death of neurons is therefore urgently required. Prerequisite is the development of diagnostic tools that identify patients at an early pre-symptomatic stage. A consortium of 21 of the most experienced AD laboratories from Europe and beyond will carry out a research project integrating data from studies with tissue cultures and genetically modified animals into a clinical investigation of demented patients. A broad array of bio-technological methods will be used. Results of these studies will lead to diagnostic screening strategies combining genetic, path physiological and biomarker information.

Fields of science

• medical and health sciences › basic medicine › neurology › dementia › alzheimer

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-3. - Key action The "Cell factory"

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

VERUM - FOUNDATION FOR BEHAVIOUR AND ENVIRONMENT

Address

Pettenkoferstr. 33
80336 Muenchen
Germany

Participants (11)

EVOTEC NEUROSCIENCES GMBH

Germany

Address

Schnackenburgallee 114
22525 Hamburg

FACULTY OF MEDICINE/UNIVERSITY HOSPITAL GOETTINGEN

Germany

Address

Robert-koch-strasse 40
37075 Goettingen

FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY VZW

Belgium

Address

Rijvisschestraat 120
9052 Zwijnaarde

FONDAZIONE CAVALIERI OTTOLENGHI

Italy

Address

San Luigi Gonzaga Hospital, Regione Gonzole 10
10043 Orbassano

FUNDACION PARA LA INVESTIGACION MEDICA APLICADA

Spain

Address

Pintor Paret 5, Oficina F
31008 Pamplona

LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH

Germany

Address

Geschwister-scholl-platz 1
80539 Muenchen

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG

Germany

Address

307,im Neuenheimer Feld 307
69120 Heidelberg

UNIVERSITY COLLEGE LONDON

United Kingdom

Address

Queen Square
WC1N 3BG London

UNIVERSITY OF AVEIRO

Portugal

Address

Campo Universitario De Santiago
3810-193 Aveiro

UNIVERSITY OF ZURICH

Switzerland

Address

Lenggstrasse 31
8029 Zurich

UPPSALA UNIVERSITY

Sweden

Address

Sankt Olofsgatan 10 B
75105 Uppsala