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Allosteric modulation of adenosine reseptors. a novel concept of receptor activation and inhibition

Objective

Alistair modulation of G protein-coupled receptors is a novel concept in receptor pharmacology. In this project a combined chemical/biological approach will be followed to design novel allotter modulators of adenosine receptors. These compounds will then be used to try and identify receptor amino acids that are involved in their binding.

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

LEIDEN UNIVERSITY
Address
55,Einsteinweg 55 Gorlaeus Laboratories
2333 CC Leiden
Netherlands