Objective
Signalling pathways and networks involving the signal compound cAMP are involved in major chronic diseases within the European community such as HIV, cancer, diabetes type II, cardiovascular disease, and genetic diseases such as diabetes incipidus and muscular dystrophies. However, no systematic approach has explored the therapeutic potential in targeting the cAMP signal pathway in conditions such as listed above with a dysregulated cAMP signal pathway. The focus of the research in the present proposal is to devise and test of therapeutic strategies based on understanding function of components of signalling networks involving the signal compound cAMP, the down-stream effectors, interaction with targeting molecules, and substrates. Specifically, work will be aimed at solving highly competitive and major tasks by joint effort leading to in vivo proof of principle experiments and drug development.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- medical and health sciences basic medicine neurology muscular dystrophies
- medical and health sciences clinical medicine endocrinology diabetes
- medical and health sciences health sciences infectious diseases RNA viruses HIV
- medical and health sciences clinical medicine cardiology cardiovascular diseases
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
0317 OSLO
Norway
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.