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Nodal signal regulation by the novel ring-protein arkadia in es cells

Objective

The objective of the proposal is to develop an assay in ES cells to study Arcadia protein function and Nodal-Nodal interaction. Nodal/Nodal signalling will be used to examine the in vitro differentiation of ES cells into germ layer specific precursors and to characterize the pathway of organiser/me endoderm induction.

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

MEDICAL RESEARCH COUNCIL
Address
Du Cane Road, Hammersmith Hospital
W12 0NN London
United Kingdom