Nodal signal regulation by the novel ring-protein arkadia in es cells

Objective

The objective of the proposal is to develop an assay in ES cells to study Arcadia protein function and Nodal-Nodal interaction. Nodal/Nodal signalling will be used to examine the in vitro differentiation of ES cells into germ layer specific precursors and to characterize the pathway of organiser/me endoderm induction.

Fields of science

• natural sciences › biological sciences › biochemistry › biomolecules › proteins

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-3. - Key action The "Cell factory"

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

MEDICAL RESEARCH COUNCIL

Address

Du Cane Road, Hammersmith Hospital
W12 0NN London
United Kingdom