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Content archived on 2024-05-15

Cell biological processes in dendritic cells determining antigen presentation by mhc class ii.

Objective

Dendrite cells (Daces) sample their environment for antigens and present antigen- derived peptides associated with MHC II to nave T cells. Antigen loading of major histocomptaiblity complex class II molecules (MHC II) in Daces is tightly regulated. This project focuses at multivesicular bodies as key regulators of this process.

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