Objective
In this application, for the first time, particulate matter (PM) will be collected from sites used in epidemiology (in addition to fresh diesel and gasoline PM) and extensively characterised physico-chemically prior to evaluation of bioactivity in in-vitro and in-vivo animals models. This unique approach will provide novel information of the oxidative and inflammatory reactivity of PM across Europe. Healthy controls, asthma and COPD patients are exposed to diesel, gasoline or selected ambient PM by inhalation/local bronchial instillation. Calculations of physico-chemical composition/source/ toxicity-health relationships thereby become feasible. The novel approach to link epidemology, toxicology and controlled human exposures will facilities a synergistic increase in the understanding of the adverse effects of PM. Moreover, it should help identify those components of PM which are of most importance for regulatory decision making within Europe.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology environmental engineering energy and fuels liquid fuels
- medical and health sciences clinical medicine pneumology asthma
- engineering and technology environmental engineering air pollution engineering
- natural sciences earth and related environmental sciences environmental sciences pollution
- medical and health sciences basic medicine toxicology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
901 87 UMEAA
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.