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Long-term potentiation and learning in freely moving psd-95 mutant mice

Objectif

Our goal is to study the relationship between learning ability NMDA receptor and LTP using the PSD 95 mutant mice. In vitro studies show that these mice exhibit larger LTPthan wild type. We will induce LTP in vivo on mutant and wild type mice before and after groups of both types will be subjected to a battery of spatial and non-spatial learning task.

Appel à propositions

Data not available

Coordinateur

MRC National Institute for Medical Research
Contribution de l’UE
Aucune donnée
Adresse
The Ridgeway Mill Hil
NW7 1AA London
Royaume-Uni

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Coût total
Aucune donnée