Objective
Skin contact with chemicals is common and can have serious consequences. There is currently insufficient data to enable regulators, employers or individuals to adequately assess the risks of dermal absorption. This project will involve European expert groups in a collaborative study to
(1) generate new high quality data on dermal absorption of potentially toxic chemicals and where relevant skin metabolism for risk assessment
(2) standardise methods using in vitro systems for predicting percutaneous penetration and
(3) compare these to relevant in vivo studies
(4) use the data generated, together with suitable literature data, to evaluate available predictive and computational models for systems for which measurements are not available. Overall the project will improve risk assessment and reduce the need for animal testing.
Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
NE1 7RU Newcastle upon Tyne
United Kingdom