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Assessment of neurobehavioural endpoints and markers of neurotoxicant exposures

Objective

Risks associated with complex food contaminants are difficult to assess especially in regard to long-term cognitive effects caused by developmental exposures. These problems will be examined in a well-characterised birth cohort where extremely high exposures to organ halogen compounds and methyl mercury are known to occur. The exposures will now be documented in detail and cover the period up to 7 years, where the children's cognitive functions will be examined. Also, sensitive blood analyses that reflect adverse effects on the brain will be developed and examined to elucidate their application as biomarkers of early cognitive effects. The results will provide information on
1) biomarker validity
2) integrated risks caused by complex exposures, and
3) susceptibility of the foetus and child to cognitive effects.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

UNIVERSITY OF SOUTHERN DENMARK - UNIVERSITY OF ODENSE
Address
Winsloewparken 17
5000 Odense
Denmark

Participants (4)

FONDAZIONE SALVATORE MAUGERI - CLINICA DEL LAVORO E DELLA RIABILITAZIONE
Italy
Address
Via Brodolini 7
27028 San Martino Siccomario
LANDESAMT FUER GESUNDHEIT UND ARBEITSSICHERHEIT DES LANDES SCHLESWIG-HOLSTEIN
Germany
Address
Hamburger Chaussee 25
24220 Flintbek
STOCKHOLM UNIVERSITET
Sweden
Address
Svante Arrhenius Vaeg, 12
106 91 Stockholm
THE FAROESE HOSPITAL SYSTEM
Faeroe Islands
Address
Sigmundargoeta 5
110 Torshavn