Assessment of neurobehavioural endpoints and markers of neurotoxicant exposures

Objective

Risks associated with complex food contaminants are difficult to assess especially in regard to long-term cognitive effects caused by developmental exposures. These problems will be examined in a well-characterised birth cohort where extremely high exposures to organ halogen compounds and methyl mercury are known to occur. The exposures will now be documented in detail and cover the period up to 7 years, where the children's cognitive functions will be examined. Also, sensitive blood analyses that reflect adverse effects on the brain will be developed and examined to elucidate their application as biomarkers of early cognitive effects. The results will provide information on
1) biomarker validity
2) integrated risks caused by complex exposures, and
3) susceptibility of the foetus and child to cognitive effects.

Fields of science

• natural sciences › biological sciences › neurobiology › cognitive neuroscience
• natural sciences › chemical sciences › inorganic chemistry › transition metals
• natural sciences › chemical sciences › inorganic chemistry › halogens
• engineering and technology › medical engineering › medical laboratory technology › laboratory samples analysis

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-4. - Key action Environment and Health

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

UNIVERSITY OF SOUTHERN DENMARK - UNIVERSITY OF ODENSE

Address

Winsloewparken 17
5000 Odense
Denmark

Participants (4)

FONDAZIONE SALVATORE MAUGERI - CLINICA DEL LAVORO E DELLA RIABILITAZIONE

Italy

Address

Via Brodolini 7
27028 San Martino Siccomario

LANDESAMT FUER GESUNDHEIT UND ARBEITSSICHERHEIT DES LANDES SCHLESWIG-HOLSTEIN

Germany

Address

Hamburger Chaussee 25
24220 Flintbek

STOCKHOLM UNIVERSITET

Sweden

Address

Svante Arrhenius Vaeg, 12
106 91 Stockholm

THE FAROESE HOSPITAL SYSTEM

Faeroe Islands

Address

Sigmundargoeta 5
110 Torshavn