Immunoassay methods will be evaluated and improved for the measurement of airborne concentrations of occupational allergens: enzymes, grain and soy flour, rodent and latex allergens. Existing immunoassays will first be compared by participants using their own assays in a, round robin TM approach. Next step will be a detailed analysis of assay differences by exchanging immune reagents and allergen standards between laboratories. Finally, optimal combinations of immune reagents, calibration standards and procedures will be developed, as a major step towards standardization of work-related allergen exposure assessment. In addition, methods will be developed, using available immune reagents, (a) for the highly sensitive measurement of short, job task-related exposures, and (b) for the rapid, semi-quantitative assessment at the worksite of allergen exposure levels.
Funding SchemeCSC - Cost-sharing contracts
EH8 9SU Edinburgh
171 77 Stockholm