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Measurement of occupational allergen exposure

Objective

Immunoassay methods will be evaluated and improved for the measurement of airborne concentrations of occupational allergens: enzymes, grain and soy flour, rodent and latex allergens. Existing immunoassays will first be compared by participants using their own assays in a, round robin TM approach. Next step will be a detailed analysis of assay differences by exchanging immune reagents and allergen standards between laboratories. Finally, optimal combinations of immune reagents, calibration standards and procedures will be developed, as a major step towards standardization of work-related allergen exposure assessment. In addition, methods will be developed, using available immune reagents, (a) for the highly sensitive measurement of short, job task-related exposures, and (b) for the rapid, semi-quantitative assessment at the worksite of allergen exposure levels.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

WISE & MUNRO LEARNING RESEARCH
Address
8,Azaleastraat 85
2565 CD Den Haag
Netherlands

Participants (5)

ATO B.V.
Netherlands
Address
Bornsesteeg 59
Wageningen
BERUFSGENOSSENSCHAFTLICHES FORSCHUNGSINSTITUT FUER ARBEITSMEDIZIN
Germany
Address
Buerkle-de-la-camp Platz 1
44789 Bochum
INSTITUT CATALA DE LA SALUT
Spain
Address
Paseo Valle De Hebron 119-129
08035 Barcelona
INSTITUTE OF OCCUPATIONAL MEDICINE LTD
United Kingdom
Address
Roxburgh Place 8
EH8 9SU Edinburgh
KAROLINSKA INSTITUTE
Sweden
Address
Solnavagen 1
171 77 Stockholm