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Content archived on 2024-05-24

Biotic and abiotic mechanisms of TSE infectivity retention and dissemination in soil

Objective

TSE contamination of soils or water, by infected herds, rotting carcasses or via the storage of rendering waste, is a matter of concern both for sustainability of European breeding activity and human health. The fate of the TSE agent in soils depends on the balance between retention, destruction and dissemination factors, either biotic or abiotic. Physico-chemical mechanisms of prion adsorption to soil mineral colloids or organo-mineral complexes and desorption conditions will be analysed with respect to protein structural entity and modifications of infectivity at both laboratory and field scales. Soil microrganisms presenting TSE infectivity lytic activity, earthworm gut enzymes as well as necrophagous insect larvae will be considered as main biotic agents affecting infectivity, dissemination and persistency. Recommendations will be deduced from scientific results by the end users associated to the consortium.

Fields of science (EuroSciVoc)

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Topic(s)

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Call for proposal

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Funding Scheme

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Coordinator

INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
EU contribution
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Address
Place Viala 2
34060 MONTPELLIER
France

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Total cost

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Participants (14)

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