Objective The nature of the transmissible agent of spongiform encephalopathies is thought to be the pathological form of the prion protein that can change the cellular form to a pathological one, also if it is orally ingested. Fish farming is becoming a very important industry. All farmed fish receive commercial food containing 40-55% protein. Animal proteins may also be present and potential occurrence of the pathological protein cannot be excluded. Since studies on the infectivity transmission in fish are very scanty, two lines of research are proposed:l) TSE pathogenesis concerning fish as targets and/or vectors for disease;2) identification of PrP and PrP-like proteins in fish genome.The second line of the research is sustained by the reason that PrP gene in fish is not yet identified and the infectivity is only possible if the cellular protein is present and can change itself onto the pathological form. Fields of science agricultural sciencesagriculture, forestry, and fisheriesfisheriesnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological scienceszoologyichthyologynatural sciencesbiological sciencesgeneticsgenomes Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-5. - Key action Sustainable Agriculture, Fisheries and Forestry Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator CENTRE FOR RESEARCH AND TECHNOLOGY HELLAS Address Charilaou 6th km - thermi road 57001 Thermi Greece See on map EU contribution € 0,00 Participants (3) Sort alphabetically Sort by EU Contribution Expand all Collapse all CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Spain EU contribution € 0,00 Address 6,eduardo cabello 6 36208 Vigo See on map NORWEGIAN SCHOOL OF VETERINARY SCIENCE Norway EU contribution € 0,00 Address Ullevaalsveien 72 Oslo See on map Links Website Opens in new window THE UNIVERSITY OF MILANO Italy EU contribution € 0,00 Address Via festa del perdono 7 20122 Milano See on map