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Structure/function Studies In Vivo Of The Estrogen Receptor-alpha

Objective

The aim is to study the importance of DNA binding of estrogen receptor-alpha (er-alpha) for transcriptional transactivation versus tranrepression in vivo. This will be done in transgenic "knock-in" mice expressing specific er-alpha mutants incapable of DNA binding.

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

Imperial Cancer Research Fund
Address
44 Lincoln's Inn Fields
WC2A 3PX London
United Kingdom

Participants (1)

Not available
Sweden