Objective
We aim to develop safer targeted gene therapy as an alternative treatment for prostate disease in the aging male population of Europe, by producing a suite of recombinant viral vectors. These should be brought into clinical trial, in the time scale of the 5th Framework, by collaboration between clinicians and scientists with experience in agrological cancer. Targeting of vectors will be achieved using promoter sequences from prostate-specific genes, and attachment to tumour cells by either antibody reedited adoption or altered capsid/envelopeproteins. Vector specificity will be verified in experimental systems, ranging forming vitro cultures of prostate carcinorna cells, tissue reconstructions, organ culture and engrafts to Phase trials. Special emphasis will be placed on safety aspects: effective targeting vectors will obviate the need for high level inoculations of recombinant virus, and in vivo immune responses will be monitored.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology genetic engineering gene therapy
- natural sciences biological sciences microbiology virology
- medical and health sciences basic medicine immunology
- medical and health sciences clinical medicine oncology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
YO10 5YW YORK
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.