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Identification of environmental and genetic risk factors for age related hearing impairment

Objective

In the 21st century, Europe will face the burden of its ageing population. The most common sensory impairment among the elderly is age related hearing impairment (ARHI). In this project, we want to identify the ethiological factors involved in ARHI, including the genetic causes, the environmental causes and the interaction between them. A large cohort of patients and controls, originating from various parts of Europe, will be subjected to audiologic evaluation, genetic analysis and a questionnaire on suspected environmental risks. We expect to identify the major susceptibility genes and clarify the role of environmental risk factors. The interaction between the different factors will be studied using neural network computing. Based upon these results, guidelines will be formulated for the prevention of ARHI.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

UNIVERSITEIT ANTWERPEN
Address
Prinsstraat 13
2000 Anvers /Antwerpen
Belgium

Participants (9)

AZIENDA OSPEDALIERA DI PADOVA
Italy
Address
Via Giustiniani 1
35128 Padova
BISPEBJERG HOSPITAL
Denmark
Address
Bispebjerk Bakke 23
2400 NV Koepenhagen
CARDIFF UNIVERSITY
United Kingdom
Address
Health Park
CF14 4XN Cardiff
ILLUMINA INC
United States
Address
9885 Towne Centre Drive
92121-1975 San Diego
RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAET BONN
Germany
Address
Sigmund-freud-strasse, 25
53105 Bonn
STICHTING KATHOLIEKE UNIVERSITEIT
Netherlands
Address
Philips Van Leydenlaan 15
6500 HB Nijmegen
UNIVERSITY HOSPITAL ANTWERP
Belgium
Address
Wilrijkstraat 10
2650 Edegem
UNIVERSITY OF OULU
Finland
Address
Kajaanintie 50
90014 Oulu
UNIVERSITY OF TAMPERE
Finland
Address
4,Medisiinarinkatu 3
33014 Tampere