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Content archived on 2024-05-15

European stroke prevention in reversible ischaemia trial (ESPRIT)

Objective

Patients who have had a transient is haemic attack or no disabling is haemic stroke of arterial origin have an annual risk of 7 to 12 % for subsequent nonfatal stroke, nonfatal myocardial infarction or death (from all vascular causes) without treatment. The standard treatment acetylsalicylic acid (ASA) prevents only 13% of these events; this is far from ideal. Data from secondary prevention trials in other cerebrovascular diseases suggest that oral anticoagulation (AC) or ASA combined with dipyridamole are more effective in the secondary prevention. Since cerebrovascular disease is one of the major European health problems, especially in the elderly, it is of utmost importance to look for more effective prevention than that by ASA. ESPRIT is a randomised, international, multicoated trial in which three treatments are compared:
a) ASA,
b) ASA combined with dipyridamole
c) AC (INR 2-3). A total of 4500 patients will be enrolled.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

Data not available

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CON - Coordination of research actions

Coordinator

UNIVERSITY MEDICAL CENTRE UTRECHT
EU contribution
No data
Address
Heidelberglaan 100
3584CX UTRECHT
Netherlands

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (14)

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