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Synthesis of analogues of lipid ii for the investigation of transglycosylases involved in bacterial cell wall biosynthesis and the development of novel antibiotics

Objective

The project aims to help clarifying the mechanism of peptidoglycan chain elongation by developing analogues of Lipid II, capable of inhibiting transglycosylases. This may lead to the discovery of novel antibiotics.

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

GENT UNIVERSITY
Address
Krijgslaan 281 S4
9000 Gent
Belgium