Objective
Reflecting the moduiar nature of eucharistic proteins, several WWW servers (e.g. PFAM, SMART, PROSITE) are dedicated to revealing domains in protein sequences: These servers have become indispensable bio informatics tools. However, there is no resource, which specifically focuses on short functional motifs (targeting peptides. docking modules. phosphorylation sites etc.). Yet these modules are Justas important for function as the larger protein domains. The reason there are no good tools is that the notify are so short that they severely over predict, only acquiring significance in the right context (e.g. KDEL functions in the ER compartment). We will address this deficit by creating and applying ELM, a comprehensive set of tools for evaluating linear notify in eukaryotlc proteins using context-based rules to reduce or eliminate false positives. ELM will be available via the www and in a package for automated genome analysis pipelines.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- natural sciencesbiological sciencesgeneticsgenomes
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Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
69012 HEIDELBERG
Germany