Objective
As a result of the BSE crisis in Europe, a number of diagnostic tests have been developed for the detection of abnormal prion protein, the putative agent of Transmissible Spongiform Encelopathies. A major problem in the study of TSE is that there are no tests able to detect the abnormal prion protein in the early stages of the disease. The aim of this proposal is to further improve and validate a method based on competitive immunoassay involving fluorescent-labelled peptides analysed by capillary electrophoresis (CE) and micro-High Performance Liquid Chromatography (µHPLC). This method which has been mainly used to detect PrPsc in sheep blood samples will be extended to the detection of bovine prions and to the pre-symptomatic detection of PrPsc in humans, from the analysis of blood and other biological samples such as cerebrospinal fluid (CSF) and urine.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences chemical sciences electrochemistry electrophoresis
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
44300 NANTES
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.