Objective
The presence of genotoxic compounds such as heterocyclic amines has been demonstrated in foodstuffs submitted to excessive heating, however, toxicologists are not yet able to agree on maximum exposure levels that can be tolerated by humans. The objective of the project was to support collaborative studies aimed at evaluating the best methods of determination of a series of genotoxic compounds in food matrices. A first intercomparison addressed the instrumental determination of 3 imidazoquinolines (IQ, Me-IQ, Me-IQx) in methanol and showed that whereas the high performance liquid chromatography (HPLC) method worked well, gas liquid chromatography (GLC) was unsatisfactory. Good correlation was obtained for the mutagenicity test (Ames test) and showed a very high mutagenic activity for these compounds. A second intercomparison on the determination of the same compounds in specially prepared meat extract has been carried out.
Concern about long term exposure to carcinogenic substances which may be present at trace levels in the human diet has greatly increased in the last decade. This has resulted in the development of government regulations, quality control and improvement of industrial food processing.
The presence of genotoxic compounds such as heterocyclic amines has been demonstrated in foodstuffs submitted to excessive heating, however, toxicologists are not yet able to agree on maximum exposure levels that can be tolerated by humans.
The objective of the project is to support collaborative studies aimed at evaluating the best methods of determination of a series of genotoxic compounds in food matrices. Reference materials will also be prepared, if necessary.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- engineering and technology other engineering and technologies food technology
- medical and health sciences health sciences nutrition
- natural sciences chemical sciences organic chemistry alcohols
- natural sciences chemical sciences organic chemistry amines
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1200 BRUXELLES
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.