Objective
The two fundamental goals of this project are:
- The further study of vanadate compounds mainly nucleotides as stable transition-state analogs for pentavalent phosphate
intermediates in reactions catalyzed by ribonuclease-T1. This involves mainly 51V-NMR and X-ray crystallography.
- The exploitation of this property of vanadate compounds to mimic transition state intermediates of phosphohydrolysis reactions, to use them, now as haptens for the production of antibodies with phosphohydrolytic capacity.
Funding Scheme
CSC - Cost-sharing contractsCoordinator
Vrije Universiteit Brussel
Address
65,Paardenstraat 65
1640 Rhode-saint-genèse
Belgium
1640 Rhode-saint-genèse
Belgium
Participants (2)
FREIE UNIVERSITAET BERLIN
Germany
Address
Kaiserswertherstrasse 16-18
Berlin
Berlin
UNIVERSITY OF HAMBURG
Germany
Address
Moorweidenstrasse, 18
20148 Hamburg
20148 Hamburg