The understanding of the molecular mechanism and regulation of eukaryotic chromosome replication is a major area of modern biological research. The main reason for this is that DNA is not self-replicating. The replication process is complex and it will be necessary to understand the mechanism of DNA replication and how it is controlled prior to obtaining a complete insight into cellular growth control throughout development and how these controls are reversed during tumorigenesis. The molecular dissection of such a complex molecular process can only be obtained by using model biological systems and a combination of biochemical and genetic experimental strategies.
Funding SchemeCSC - Cost-sharing contracts
NW7 1AA London