Objective
Sunscreens, made in Europe are a very important product on the international market.
Quantitative data, and an exact knowledge of the protective efficacy covering the complete range of potentially harmful UV-effects, including erythema, UV-induced immune suppression and DNA damage, are an important prerequisite to improve the competitive position of the European Cosmetic Industry. This aim shall reached in the proposed project developing and testing a new in vivo measurement method to assess the efficacy of sunscreens in the UVB and UVA range in an non-invasive manner, and to correlate the measured spectral data with UV induced biological responses. As one result of the project work a higher security will be obtained determining the protective properties of sunscreens in the relation between solar radiation and skin cancer. The industrial partners will guarantee that the work is nearly connected with the needs of the industry.
The expected results shall taken as a proposal for pre-standards in connection with COLIPA and CEN.
The proposed project combines the method of tape stripping with UV/VIS spectroscopic measurements. By this way it is possible to determine the thickness of the horny layer as the prerequisite to measure the penetration depth of filter substances as well as the spectral UV intensity distribution inside stratum corneum. The obtained results will be reviewed by different modern analytical methods usually applied in industrial research assessing the efficacy of sunscreens and the behaviour of UV filter.
The necessary relation of the measured intensities to the biological responses is ensured investigating the UV induced DNA damage and the immune suppression. This guarantees that the determination of the efficacy of sunscreens includes not only the formation of erythema, as done presently, but a broader range of potentially harmful UV effects. The planned investigations will include volunteers of skin type I -IV.
The expected results shall be a prerequisite to the requirement for sunscreens with an optimal protection against these critical damages and the requirement for a new reference method to test sunscreens.
The planned results will be applied mainly in the industrial research using the additional criteria, proposed by the investigated method, to optimise the development of sunscreens. Thus, the objectives of the project shall yield important contributions to avoid a further rise of sun associated incidence of skin cancer, as an important step to improve human health in the future.The issues of the proposed project shall make available a simple non-invasive method as a prenormative proposal for standards. Supporting by this way the European industry in the timely production of products of requisite quality and at an acceptable price by the development of improved measurement and testing techniques.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine oncology skin cancer
- natural sciences biological sciences genetics DNA
- natural sciences earth and related environmental sciences atmospheric sciences meteorology solar radiation
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
10117 Berlin
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.