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Content archived on 2024-04-15

STUDIES ON THE MECHANISM(S) OF THE ANTITUMOR ACTION OF INTERFERON

Objective


Results achieved can be summarised as follows:
definition of the optimal treatment regimens with interferon in tumour bearing mice transplanted with highly malignant syngeneic tumour cells;
identification of a potent antimetastatic effect of interferon alpha beta in mice injected with highly metastatic Friend leukaemia cells;
evaluation of the in vivo relevance of the host mediated mechanisms in the antitumour effects of interferon in mice injected with interferon resistant Friend leukaemia cells.

Topic(s)

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Call for proposal

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Coordinator

ISTITUTO SUPERIORE DI SANITA
EU contribution
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Viale Regina Elena 299
00161 ROMA
Italy

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Participants (1)