Objective An appropriate invertebrate nervous system, which is relatively small and amenable to study at the level of single identified cells, has been used as a model for the analysis of neuronal mechanisms which control locomotion. 3 main neuronal processes have been investigated: the coding of locomotory movements by afferent signals, the modulation of reflexes during active movements and the coordination of different locomotory rhythms. An in vitro preparation of the isolated nervous system of the crayfish, which reliably expresses both reflex responses and rhythmical motor outputs has been developed. With this system it has been possible to use intracellular techniques to study the synaptic mechanisms of sensory motor interactions at the level of single neurones. An important factor in the success of these studies has been the wide use of computational procedures to analyse the neurophysiological signals. Signal averaging procedures have allowed the identification of synaptic interactions, while a suite of customised nerve spike software has allowed the analysis of rhythmical bursts of nerve activity in terms of their temporal parameters and phase relationships. Fields of science natural sciencesbiological sciencesneurobiologynatural sciencescomputer and information sciencessoftware Programme(s) FP1-STIMULATION 1C - Plan (EEC) to stimulate European scientific and technical cooperation and interchange, 1985-1988 Topic(s) Data not available Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator UNIVERSITY OF GLASGOW Address University avenue Glasgow United Kingdom See on map EU contribution € 0,00 Participants (2) Sort alphabetically Sort by EU Contribution Expand all Collapse all Centre National de la Recherche Scientifique (CNRS) France EU contribution € 0,00 Address Place du docteur peyneau 33120 Arcachon See on map University of Bristol United Kingdom EU contribution € 0,00 Address Senate house tyndall avenue BS8 1TH Bristol See on map Links Website Opens in new window
