The long-term impact on morbidity and mortality of measles infection

Objective

Small ruminants are the most important farm animals in Syria. Respiratory disorders are among the most important problems associated with small ruminant health, causing high morbidity and mortality. The major cause of mortality is acute pneumonia with suspected viral etiology, complicated with the eventual synergy with lungworms.

Only fragmentary information is currently available on viral respiratory infections of small ruminants in Syria but surveys of parasitic bronchitis in syrian sheep showed heavy infestation of lungworms. Until now, only an interaction between bacteria and lungworms has been demonstrated and no studies have been conducted on how they interact with viruses.
The purpose of the proposed research is:
- undertake an epidemiological survey for viruses affecting the respiratory system and lungworms extended to the entire country - conduct studies on anatomo-pathological changes in lungs of sheep - infect experimentally sheep with viral pathogens combined with lungworm infection
- assess the synergy between viruses and lungworms and establish efficient prophylactic measures for small ruminants in Syria - transfer the technology for viral diagnostic methodology to the Veterinary Faculty of Hama.

Fields of science

• medical and health sciences › clinical medicine › pneumology
• social sciences › sociology › demography › mortality
• natural sciences › biological sciences › microbiology › bacteriology
• natural sciences › biological sciences › microbiology › virology
• medical and health sciences › health sciences › infectious diseases › RNA viruses › coronaviruses

Programme(s)

• FP3-STD 3 - Specific research and technological development programme (EEC) in the field of the life sciences and technologies for developing countries, 1990-1994

Topic(s)

Data not available

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

STATENS SERUM INSTITUT

Address

5,artillerivej 5
2300 Koepenhagen
Denmark

Participants (4)

Institut Français de Recherche Scientifique pour le Développement en Coopération - ORSTOM

France

Address

Rue La Fayette 213
75010 Paris

International Centre for Diarrhoeal Disease Research

Bangladesh

Address

1000 Dhaka

Københavns Universitet

Denmark

Address

1,frue Plads
1168 København K

Medical Research Council (MRC)

United Kingdom

Address

20 Park Crescent
W1N 4AL London