Direct Alkylation of Saturated Cyclic Amines via catalytic C-H Functionalization

Projektinformationen

DASCA

ID Finanzhilfevereinbarung: 331366

Abgeschlossenes Projekt

Startdatum 1 März 2013

Enddatum 28 Februar 2015

Finanziert unter

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 169 800,00

EU-Beitrag € 169 800,00

Koordiniert durch

UNIVERSITEIT ANTWERPEN
Belgium

Ziel

"Direct conversion of C-H into C-C bonds is arguably indispensable in modern organic chemistry, as it allows for obtaining target compounds which are otherwise only accessible via lengthy procedures involving multi-step synthesis. Catalytic C-H functionalization is the most attractive approach to achieve this goal, as it does not require stoichiometric amounts of activating reagent. This research proposal aims to develop direct transition metal-catalyzed functionalizations of C(sp3)–H bonds in saturated nitrogen-based heterocycles, with a particular focus on compatibility with a very broad range of functional groups, regioselectivity and stereoselectivity. Towards this goal, insertion reactions with substituted alkenes featuring a variety of functional groups will be explored. The development of such a technology offers an important contribution to novel, improved and more sustainable synthetic pathways and is expected to be highly warranted for drug discovery purposes."

Wissenschaftliches Gebiet

• medical and health sciences › basic medicine › pharmacology and pharmacy › drug discovery
• natural sciences › chemical sciences › organic chemistry › amines

Programm/Programme

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• FP7-PEOPLE-2012-IIF - Marie Curie Action: "International Incoming Fellowships"

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2012-IIF
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IIF - International Incoming Fellowships (IIF)

Koordinator

UNIVERSITEIT ANTWERPEN

Kontakt Verwaltung

Anne Adams (Mrs.)

• EU-Beitrag: € 169 800,00
• Adresse: PRINSSTRAAT 13 ; 2000 Antwerpen ; Belgien
• Region: Vlaams Gewest › Prov. Antwerpen › Arr. Antwerpen
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten