Skip to main content

Neuroimaging platform for characterisation of metabolic co-morbidities in psychotic disorders

Objetivo

The theme of this collaborative project is development and application of neuroimaging and bioinformatics tools to study lipid metabolism as a common pathogenic link between psychotic disorders and its metabolic co-morbidities. The overall objective is to identify, prioritize and evaluate multi-modal blood and neuroimaging markers with diagnostic potential for prediction and monitoring of psychotic disorders and associated metabolic co-morbidities. We aim to (1) optimise a multidisciplinary approach for combining positron emission tomography (PET) and magnetic resonance imaging (MRI) with metabolomics approaches, (2) develop a PET-method for exploring endocannabinoid pathways in early psychosis in longitudinal study setting, and (3) develop combined PET-MRI biomarker methodology for psychiatric disorders by studying neurotransmitter interactions with multiple PET scan and MRI sequences. The balance of two or more neurotransmitter systems may function as a novel biomarker in these disorders. The expected impacts are (1) etiopathogenic understanding, (2) new validated multi-modal markers for early disease detection and monitoring, (3) new tools for the identification of subjects who may benefit from specific treatment (4) discovery of new avenues for disease prevention and therapy, and (5) new tools and processes for applying brain imaging in personalised medicine. The consortium brings together clinicians, researchers and industry partners in the domains of psychiatry, neuroimaging, metabolic research, systems biology and bioinformatics.

Convocatoria de propuestas

FP7-HEALTH-2013-INNOVATION-1
Consulte otros proyectos de esta convocatoria

Coordinador

TURUN YLIOPISTO
Dirección
Yliopistonmaki
20014 Turku
Finlandia
Tipo de actividad
Higher or Secondary Education Establishments
Aportación de la UE
€ 957 512,35

Participantes (10)

TEKNOLOGIAN TUTKIMUSKESKUS VTT

La participación finalizó

Finlandia
Dirección
Tekniikantie 4 A
02044 VTT Espoo
Tipo de actividad
Research Organisations
PHILIPS TECHNOLOGIE GMBH

La participación finalizó

Alemania
Dirección
Luebeckertordamm 5
20099 Hamburg
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BIOMAX INFORMATICS AG
Alemania
Aportación de la UE
€ 673 360
Dirección
Robert Koch Strasse 2
82152 Planegg
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SERVICIO MADRILENO DE SALUD
España
Aportación de la UE
€ 430 950
Dirección
Plaza Carlos Trias Bertran 7
28020 Madrid
Tipo de actividad
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
NOVO NORDISK INVEST 4 A/S

La participación finalizó

Dinamarca
Aportación de la UE
€ 373 788,65
Dirección
Novo Alle 1
2880 Bagsvaerd
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
TERVEYDEN JA HYVINVOINNIN LAITOS
Finlandia
Aportación de la UE
€ 425 548
Dirección
Mannerheimintie 166
00271 Helsinki
Tipo de actividad
Research Organisations
PHILIPS GMBH
Alemania
Aportación de la UE
€ 596 952
Dirección
Rontgenstrasse 22
22335 Hamburg
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
KING'S COLLEGE LONDON
United Kingdom
Aportación de la UE
€ 557 735
Dirección
Strand
WC2R 2LS London
Tipo de actividad
Higher or Secondary Education Establishments
TEKNOLOGIAN TUTKIMUSKESKUS VTT OY
Finlandia
Aportación de la UE
€ 178 273
Dirección
Tekniikantie 21
02150 Espoo
Tipo de actividad
Research Organisations
OREBRO UNIVERSITY
Suecia
Aportación de la UE
€ 39 750
Dirección
Fakultetsgatan 1
70182 Orebro
Tipo de actividad
Higher or Secondary Education Establishments