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A dedicated trimodality (PET/MR/EEG) imaging tool for schizophrenia

Objective

"Schizophrenia is a severe mental disorder that manifests early in life and imposes a high social and economic burden on European societies. An imaging tool that enables the diagnosis of schizophrenia during early development is extremely desirable and is requested by the clinical community in order to make the management of the disease more effective.
TRIMAGE aims to optimise and validate an integrated diagnostic solution including simultaneous PET/MR/EEG imaging and specific biomarkers to provide the clinicians an effective tool for the diagnosis and choice of treatment of schizophrenia and other mental health disorders.
Specific biomarkers using information from PET/MR, fMRI/EEG and PET/MR/EEG will be used to define the signature of the disease. The imaging hardware will be engineered with the intent of making the instrument a cost-effective and ""beyond the state of the art"" commercial product so as to provide a toolset for the diagnosis of patients in most clinical psychiatric centres.
The instrument will comprise a 1.5 T cryogen-free, very compact superconducting magnet, a PET insert based on silicon photomultiplier with better performances (2 mm FWHM spatial resolution, 14% sensitivity at the center of the field of view) than any available clinical PET scanner and a fully integrated EEG. The adopted technology will reduce cost, simplify safety management, improve patient comfort and boost performance with respect to state of the art MRI and PET brain imagers.
The tool design and construction requires scientific and technological developments in both the physical and medical fields: the work plan counts on the cooperation of highly qualified academic institutions and research centres with a major R&D contribution coming from four high technology European SMEs and Large Companies."

Field of science

  • /natural sciences/chemical sciences/inorganic chemistry/inorganic compounds
  • /medical and health sciences/clinical medicine/psychiatry/schizophrenia

Call for proposal

FP7-HEALTH-2013-INNOVATION-1
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

UNIVERSITA DI PISA
Address
Lungarno Pacinotti 43/44
56126 Pisa
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 117 094,02
Administrative Contact
Sandra Masi (Mrs.)

Participants (10)

TECHNOLOGIKO EKPAIDEFTIKO IDRYMA ATHINAS
Greece
EU contribution
€ 239 240
Address
Agiou Spyridonos 28 Kai Milou 1
122 10 Aigaleo
Activity type
Higher or Secondary Education Establishments
Administrative Contact
George Loudos (Prof.)
FORSCHUNGSZENTRUM JULICH GMBH
Germany
EU contribution
€ 755 820
Address
Wilhelm Johnen Strasse
52428 Julich
Activity type
Research Organisations
Administrative Contact
Anke Krüger (Mrs.)
UNIVERSITAETSKLINIKUM AACHEN
Germany
EU contribution
€ 285 600
Address
Pauwelsstrasse 30
52074 Aachen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Irene Neuner (Dr.)
KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
Germany
EU contribution
€ 495 120
Address
Ismaninger Strasse 22
81675 Muenchen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Renate Rädlein
UNIVERSITAT ZURICH
Switzerland
EU contribution
€ 279 600
Address
Ramistrasse 71
8006 Zürich
Activity type
Other
Administrative Contact
Wolfram Kawohl (Dr.)
ISTITUTO NAZIONALE DI FISICA NUCLEARE
Italy
EU contribution
€ 285 840
Address
Via Enrico Fermi 54
00044 Frascati
Activity type
Research Organisations
Administrative Contact
Rosaria Porcu (Dr.)
ADVANSID SRL
Italy
EU contribution
€ 154 500
Address
Via Sommarive 18 Frazione Povo
38123 Trento
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Sabrina Colpo (Ms.)
WEEROC SAS
France
EU contribution
€ 364 800
Address
Rue Des Fosses 9
91100 Corbeil-essonnes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Julien Fleury (Mr.)
raytest Isotopenmessgeraete GmbH

Participation ended

Germany
EU contribution
€ 171 721,98
Address
Benzstrasse 4
75334 Straubenhardt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Oliver Dietzel (Mr.)
RS2D
France
EU contribution
€ 1 845 044
Address
13 Rue Vauban
67450 Mundolsheim
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Rémy Schimpf (Mr.)