CORDIS
EU research results

CORDIS

English EN

A dedicated trimodality (PET/MR/EEG) imaging tool for schizophrenia

Project information

Grant agreement ID: 602621

Status

Closed project

  • Start date

    1 December 2013

  • End date

    30 November 2018

Funded under:

FP7-HEALTH

  • Overall budget:

    € 7 975 902,67

  • EU contribution

    € 5 994 380

Coordinated by:

UNIVERSITA DI PISA

Italy

Objective

"Schizophrenia is a severe mental disorder that manifests early in life and imposes a high social and economic burden on European societies. An imaging tool that enables the diagnosis of schizophrenia during early development is extremely desirable and is requested by the clinical community in order to make the management of the disease more effective.
TRIMAGE aims to optimise and validate an integrated diagnostic solution including simultaneous PET/MR/EEG imaging and specific biomarkers to provide the clinicians an effective tool for the diagnosis and choice of treatment of schizophrenia and other mental health disorders.
Specific biomarkers using information from PET/MR, fMRI/EEG and PET/MR/EEG will be used to define the signature of the disease. The imaging hardware will be engineered with the intent of making the instrument a cost-effective and ""beyond the state of the art"" commercial product so as to provide a toolset for the diagnosis of patients in most clinical psychiatric centres.
The instrument will comprise a 1.5 T cryogen-free, very compact superconducting magnet, a PET insert based on silicon photomultiplier with better performances (2 mm FWHM spatial resolution, 14% sensitivity at the center of the field of view) than any available clinical PET scanner and a fully integrated EEG. The adopted technology will reduce cost, simplify safety management, improve patient comfort and boost performance with respect to state of the art MRI and PET brain imagers.
The tool design and construction requires scientific and technological developments in both the physical and medical fields: the work plan counts on the cooperation of highly qualified academic institutions and research centres with a major R&D contribution coming from four high technology European SMEs and Large Companies."

Coordinator

UNIVERSITA DI PISA

Address

Lungarno Pacinotti 43/44
56126 Pisa

Italy

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 117 094,02

Administrative Contact

Sandra Masi (Mrs.)

Participants (10)

TECHNOLOGIKO EKPAIDEFTIKO IDRYMA ATHINAS

Greece

EU Contribution

€ 239 240

FORSCHUNGSZENTRUM JULICH GMBH

Germany

EU Contribution

€ 755 820

UNIVERSITAETSKLINIKUM AACHEN

Germany

EU Contribution

€ 285 600

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN

Germany

EU Contribution

€ 495 120

UNIVERSITAT ZURICH

Switzerland

EU Contribution

€ 279 600

ISTITUTO NAZIONALE DI FISICA NUCLEARE

Italy

EU Contribution

€ 285 840

ADVANSID SRL

Italy

EU Contribution

€ 154 500

WEEROC SAS

France

EU Contribution

€ 364 800

raytest Isotopenmessgeraete GmbH

Germany

EU Contribution

€ 171 721,98

RS2D

France

EU Contribution

€ 1 845 044

Project information

Grant agreement ID: 602621

Status

Closed project

  • Start date

    1 December 2013

  • End date

    30 November 2018

Funded under:

FP7-HEALTH

  • Overall budget:

    € 7 975 902,67

  • EU contribution

    € 5 994 380

Coordinated by:

UNIVERSITA DI PISA

Italy