Objective
The aim of this project is to use the ninespine stickleback as a model to understand the relative importance of natural selection and random demographic events in shaping the evolution of ecologically relevant complex traits; harness the demographic history of the stickleback to detect complex genetic interactions affecting complex traits; improve the empirical understanding of the genetics of complex traits, and explore the effect of copy number variation (CNV) on complex traits. I will employ the latest genomic technologies to produce a panel of Single Nucleotide Polymorphisms (SNPs) to map Quantitative Trait Loci (QTL). I will test the effects of selection and demographic history with Qst-Fst analysis, to determine which genomic regions are subject to selection across populations and which ones have population specific effects. Identifying population specific QTL will allow improving our empirical understanding of how QTL interact with their genetic background, providing novel insight to understand context-dependent genetic effects. I will use the data generated for QTL mapping to detect the presence of CNV, and I will test the relative importance of this kind of genetic variability in the establishment of quantitative traits variability. These results are expected to significantly impact on our current understanding of the distribution of adaptive variation in the wild, and lead to significant advancements in the theoretical framework of adaptive quantitative genetics. In addition, these results will have a direct impact in informing selective and breeding practices of domesticated animals and plants, to balance the need of preserving genetic variability while allowing for an efficient genetic and phenotypic response to artificial selection. It will also provide us greater knowledge to effectively manage endangered species fragmented in disjointed populations which are simultaneously facing both genetic diversity loss and anthropic and climate change selection.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agricultural biotechnology marker assisted selection
- humanities history and archaeology history
- natural sciences biological sciences genetics nucleotides
- natural sciences earth and related environmental sciences atmospheric sciences climatology climatic changes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
00014 Helsinki
Finland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.