Deliverables Documents, reports (4) Quality and contingency A quality and contingency plan is ready to be distributed Report and management activities A report on data mangement activities will be published Communication and dissemination plan A well-defined Communication and Dissemination plan, including communication objectives, messages, target audience and the tools/methods to reach the widest audience, will be defined and published. The Project image will be presented by month 6 The communication and dissemination activities carried out along the Project life, including Scientific conferences and publications, will be published by month 48 Report on existing standards and standardization landscape A report describing the existing standards and standardization landscape will be published Websites, patent fillings, videos etc. (1) Project website The Project website will be designed and ready to work Publications Peer reviewed articles (41) It Takes Two to Tango: Coupling of Angiogenesis and Osteogenesis for Bone Regeneration Author(s): Andrea Grosso, Maximilian G. Burger, Alexander Lunger, Dirk J. Schaefer, Andrea Banfi, Nunzia Di Maggio Published in: Frontiers in Bioengineering and Biotechnology, Issue 5, 2017, Page(s) 68, ISSN 2296-4185 Publisher: Frontiers Media S.A. DOI: 10.3389/fbioe.2017.00068 Biomimetic click assembled multilayer coatings exhibiting responsive properties Author(s): Maria P. Sousa, Israel Gonzalez de Torre, Mariana B. Oliveira, José C. Rodríguez-Cabello, João F. Mano Published in: Materials Today Chemistry, Issue 4, 2017, Page(s) 150-163, ISSN 2468-5194 Publisher: Elsevier Ltd. DOI: 10.1016/j.mtchem.2017.04.001 Control of angiogenesis and host response by modulating the cell adhesion properties of an Elastin-Like Recombinamer-based hydrogel Author(s): Sebastian Manuel Staubli, Giulia Cerino, Israel Gonzalez De Torre, Matilde Alonso, Daniel Oertli, Friedrich Eckstein, Katharina Glatz, José Carlos Rodríguez Cabello, Anna Marsano Published in: Biomaterials, Issue 135, 2017, Page(s) 30-41, ISSN 0142-9612 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.biomaterials.2017.04.047 Bioactive scaffolds based on elastin-like materials for wound healing Author(s): J. Carlos Rodríguez-Cabello, I. González de Torre, A. Ibañez-Fonseca, M. Alonso Published in: Advanced Drug Delivery Reviews, Issue 129, 2018, Page(s) 118-133, ISSN 0169-409X Publisher: Elsevier BV DOI: 10.1016/j.addr.2018.03.003 Beta Cell Death by Cell-free DNA and Outcome After Clinical Islet Transplantation Author(s): Boris L. Gala-Lopez, Daniel Neiman, Tatsuya Kin, Doug O’Gorman, Andrew R. Pepper, Andrew J. Malcolm, Sheina Pianzin, Peter A. Senior, Patricia Campbell, Benjamin Glaser, Yuval Dor, Ruth Shemer, A.M. James Shapiro Published in: Transplantation, Issue 102/6, 2018, Page(s) 978-985, ISSN 0041-1337 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1097/TP.0000000000002083 Biocompatibility of two model elastin-like recombinamer-based hydrogels formed through physical or chemical cross-linking for various applications in tissue engineering and regenerative medicine Author(s): Arturo Ibáñez-Fonseca, Teresa L. Ramos, Israel González de Torre, Luis Ignacio Sánchez-Abarca, Sandra Muntión, Francisco Javier Arias, María Consuelo del Cañizo, Matilde Alonso, Fermín Sánchez-Guijo, José Carlos Rodríguez-Cabello Published in: Journal of Tissue Engineering and Regenerative Medicine, Issue 12/3, 2018, Page(s) e1450-e1460, ISSN 1932-6254 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/term.2562 Random and oriented electrospun fibers based on a multicomponent, in situ clickable elastin-like recombinamer system for dermal tissue engineering Author(s): Israel González de Torre, Arturo Ibáñez-Fonseca, Luis Quintanilla, Matilde Alonso, José-Carlos Rodríguez-Cabello Published in: Acta Biomaterialia, Issue 72, 2018, Page(s) 137-149, ISSN 1742-7061 Publisher: Elsevier BV DOI: 10.1016/j.actbio.2018.03.027 Islet Encapsulation: Physiological Possibilities and Limitations Author(s): Olle Korsgren Published in: Diabetes, Issue 66/7, 2017, Page(s) 1748-1754, ISSN 0012-1797 Publisher: American Diabetes Association DOI: 10.2337/db17-0065 Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus Author(s): Per-Ola Carlsson, Daniel Espes, Amir Sedigh, Avi Rotem, Baruch Zimerman, Helena Grinberg, Tali Goldman, Uriel Barkai, Yuval Avni, Gunilla T. Westermark, Lina Carlbom, Håkan Ahlström, Olof Eriksson, Johan Olerud, Olle Korsgren Published in: American Journal of Transplantation, Issue 18/7, 2018, Page(s) 1735-1744, ISSN 1600-6135 Publisher: Blackwell Publishing Inc. DOI: 10.1111/ajt.14642 Glucose Effectiveness Author(s): Erik Korsgren, Olle Korsgren Published in: Transplantation, Issue 100/1, 2016, Page(s) 111-115, ISSN 0041-1337 Publisher: Lippincott Williams & Wilkins Ltd. DOI: 10.1097/TP.0000000000000900 Chitosan-Recombinamer Layer-by-Layer Coatings for Multifunctional Implants Author(s): Jeevan Govindharajulu, Xi Chen, Yuping Li, Jose Rodriguez-Cabello, Mrinal Battacharya, Conrado Aparicio Published in: International Journal of Molecular Sciences, Issue 18/2, 2017, Page(s) 369, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms18020369 Förster Resonance Energy Transfer-Paired Hydrogel Forming Silk-Elastin-Like Recombinamers by Recombinant Conjugation of Fluorescent Proteins Author(s): Arturo Ibáñez-Fonseca, Matilde Alonso, Francisco Javier Arias, José Carlos Rodríguez-Cabello Published in: Bioconjugate Chemistry, Issue 28/3, 2017, Page(s) 828-835, ISSN 1043-1802 Publisher: American Chemical Society DOI: 10.1021/acs.bioconjchem.6b00738 Intrafibrillar Mineralization of Self-Assembled Elastin-Like Recombinamer Fibrils Author(s): Yuping Li, Jose Carlos Rodriguez-Cabello, Conrado Aparicio Published in: ACS Applied Materials & Interfaces, Issue 9/7, 2017, Page(s) 5838-5846, ISSN 1944-8244 Publisher: American Chemical Society DOI: 10.1021/acsami.6b15285 Cross-linking of a biopolymer-peptide co-assembling system Author(s): Karla E. Inostroza-Brito, Estelle C. Collin, Anna Majkowska, Sherif Elsharkawy, Alistair Rice, Armando E. del Río Hernández, Xin Xiao, José Rodríguez-Cabello, Alvaro Mata Published in: Acta Biomaterialia, Issue 58, 2017, Page(s) 80-89, ISSN 1742-7061 Publisher: Elsevier BV DOI: 10.1016/j.actbio.2017.05.043 Human adipose derived stem cells are superior to human osteoblasts (HOB) in bone tissue engineering on a collagen-fibroin-ELR blend Author(s): Esen Sayin, Rosti Hama Rashid, José Carlos Rodríguez-Cabello, Ahmed Elsheikh, Erkan Türker Baran, Vasif Hasirci Published in: Bioactive Materials, Issue 2/2, 2017, Page(s) 71-81, ISSN 2452-199X Publisher: Royal Society of Chemistry DOI: 10.1016/j.bioactmat.2017.04.001 Recombinant DNA technology and click chemistry: a powerful combination for generating a hybrid elastin-like-statherin hydrogel to control calcium phosphate mineralization Author(s): Mohamed Hamed Misbah, Mercedes Santos, Luis Quintanilla, Christina Günter, Matilde Alonso, Andreas Taubert, José Carlos Rodríguez-Cabello Published in: Beilstein Journal of Nanotechnology, Issue 8, 2017, Page(s) 772-783, ISSN 2190-4286 Publisher: Beilstein-Institut Zur Forderung der Chemischen Wissenschaften DOI: 10.3762/bjnano.8.80 Regeneration of hyaline cartilage promoted by xenogeneic mesenchymal stromal cells embedded within elastin-like recombinamer-based bioactive hydrogels Author(s): David Pescador, Arturo Ibáñez-Fonseca, Fermín Sánchez-Guijo, Jesús G. Briñón, Francisco Javier Arias, Sandra Muntión, Cristina Hernández, Alessandra Girotti, Matilde Alonso, María Consuelo del Cañizo, José Carlos Rodríguez-Cabello, Juan Francisco Blanco Published in: Journal of Materials Science: Materials in Medicine, Issue 28/8, 2017, Page(s) 115, ISSN 0957-4530 Publisher: Kluwer Academic Publishers DOI: 10.1007/s10856-017-5928-1 PHBV wet spun scaffold coated with ELR-REDV improves vascularization for bone tissue engineering Author(s): Ayse Selcen Alagoz, Jose Carlos Rodriguez-Cabello, Vasif Hasirci Published in: Biomedical Materials, 2018, ISSN 1748-6041 Publisher: Institute of Physics Publishing DOI: 10.1088/1748-605X/aad139 Protein disorder–order interplay to guide the growth of hierarchical mineralized structures Author(s): Sherif Elsharkawy, Maisoon Al-Jawad, Maria F. Pantano, Esther Tejeda-Montes, Khushbu Mehta, Hasan Jamal, Shweta Agarwal, Kseniya Shuturminska, Alistair Rice, Nadezda V. Tarakina, Rory M. Wilson, Andy J. Bushby, Matilde Alonso, Jose C. Rodriguez-Cabello, Ettore Barbieri, Armando del Río Hernández, Molly M. Stevens, Nicola M. Pugno, Paul Anderson, Alvaro Mata Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-018-04319-0 Tuning the stiffness of surfaces by assembling genetically engineered polypeptides with tailored amino acid sequence Author(s): Rui R. Costa, Miguel González-Pérez, Marcos Herrero-Gutiérrez, Ricardo A. Pires, Matilde Alonso, J. Carlos Rodriguez-Cabello, Rui L. Reis, Iva Pashkuleva Published in: Biomacromolecules, 2018, Page(s) 3401-3411, ISSN 1525-7797 Publisher: American Chemical Society DOI: 10.1021/acs.biomac.8b00723 Macroporous click-elastin-like hydrogels for tissue engineering applications Author(s): Alicia Fernández-Colino, Frederic Wolf, Hans Keijdener, Stephan Rütten, Thomas Schmitz-Rode, Stefan Jockenhoevel, J. Carlos Rodríguez-Cabello, Petra Mela Published in: Materials Science and Engineering: C, Issue 88, 2018, Page(s) 140-147, ISSN 0928-4931 Publisher: Elsevier BV DOI: 10.1016/j.msec.2018.03.013 Cartilage Regeneration in Preannealed Silk Elastin-Like Co-Recombinamers Injectable Hydrogel Embedded with Mature Chondrocytes in an Ex Vivo Culture Platform Author(s): Filippo Cipriani, Melanie Krüger, Israel Gonzalez de Torre, Luis Quintanilla Sierra, Matilde Alonso Rodrigo, Linda Kock, José Carlos Rodriguez-Cabello Published in: Biomacromolecules, Issue 19/11, 2018, Page(s) 4333-4347, ISSN 1525-7797 Publisher: American Chemical Society DOI: 10.1021/acs.biomac.8b01211 A transferrin receptor-binding mucoadhesive elastin-like recombinamer: In vitro and in vivo characterization Author(s): Constancio Gonzalez-Obeso, Alessandra Girotti, J. Carlos Rodriguez-Cabello Published in: Acta Biomaterialia, Issue 88, 2019, Page(s) 241-250, ISSN 1742-7061 Publisher: Elsevier BV DOI: 10.1016/j.actbio.2019.02.027 Bicyclic RGD peptides with high integrin α v β 3 and α 5 β 1 affinity promote cell adhesion on elastin-like recombinamers Author(s): Filippo Cipriani, Dominik Bernhagen, Carmen García-Arévalo, Israel González de Torre, Peter Timmerman, José Carlos Rodríguez-Cabello Published in: Biomedical Materials, Issue 14/3, 2019, Page(s) 035009, ISSN 1748-605X Publisher: IOP Publishing DOI: 10.1088/1748-605x/aafd83 Bioinspired baroplastic glycosaminoglycan sealants for soft tissues Author(s): Rui R. Costa, Diana Soares da Costa, Rui L. Reis, Iva Pashkuleva Published in: Acta Biomaterialia, Issue 87, 2019, Page(s) 108-117, ISSN 1742-7061 Publisher: Elsevier BV DOI: 10.1016/j.actbio.2019.01.040 Spatial control and cell adhesion selectivity on model gold surfaces grafted with elastin-like recombinamers Author(s): Tatjana Flora, I. González de Torre, Luis Quintanilla, M. Alonso, J. Carlos Rodríguez-Cabello Published in: European Polymer Journal, Issue 106, 2018, Page(s) 19-29, ISSN 0014-3057 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.eurpolymj.2018.06.026 A novel lipase-catalyzed method for preparing ELR-based bioconjugates Author(s): Ana M. Testera, Mercedes Santos, Alessandra Girotti, F. Javier Arias, J. Manuel Báñez, Matilde Alonso, J. Carlos Rodríguez-Cabello Published in: International Journal of Biological Macromolecules, Issue 121, 2019, Page(s) 752-759, ISSN 0141-8130 Publisher: Elsevier BV DOI: 10.1016/j.ijbiomac.2018.10.028 Tethering QK peptide to enhance angiogenesis in elastin-like recombinamer (ELR) hydrogels Author(s): Tatjana Flora, I. González de Torre, M. Alonso, J. Carlos Rodríguez-Cabello Published in: Journal of Materials Science: Materials in Medicine, Issue 30/2, 2019, ISSN 0957-4530 Publisher: Kluwer Academic Publishers DOI: 10.1007/s10856-019-6232-z Coating Strategies Using Layer-by-layer Deposition for Cell Encapsulation Author(s): Mariana B. Oliveira, Javad Hatami, João F. Mano Published in: Chemistry - An Asian Journal, Issue 11/12, 2016, Page(s) 1753-1764, ISSN 1861-4728 Publisher: Wiley - V C H Verlag GmbbH & Co. DOI: 10.1002/asia.201600145 Co-assembly, spatiotemporal control and morphogenesis of a hybrid protein–peptide system Author(s): Karla E. Inostroza-Brito, Estelle Collin, Orit Siton-Mendelson, Katherine H. Smith, Amàlia Monge-Marcet, Daniela S. Ferreira, Raúl Pérez Rodríguez, Matilde Alonso, José Carlos Rodríguez-Cabello, Rui L. Reis, Francesc Sagués, Lorenzo Botto, Ronit Bitton, Helena S. Azevedo, Alvaro Mata Published in: Nature Chemistry, Issue 7/11, 2015, Page(s) 897-904, ISSN 1755-4330 Publisher: Nature Publishing Group DOI: 10.1038/nchem.2349 Multilayered Films Produced by Layer-by-Layer Assembly of Chitosan and Alginate as a Potential Platform for the Formation of Human Adipose-Derived Stem Cell aggregates Author(s): Javad Hatami, Sandra Silva, Mariana Oliveira, Rui Costa, Rui Reis, João Mano Published in: Polymers, Issue 9/12, 2017, Page(s) 440, ISSN 2073-4360 Publisher: MPDI Open Access Publishing DOI: 10.3390/polym9090440 3D silicon doped hydroxyapatite scaffolds decorated with Elastin-like Recombinamers for bone regenerative medicine Author(s): Mercedes Vila, Ana García, Alessandra Girotti, Matilde Alonso, Jose Carlos Rodríguez-Cabello, Arlyng González-Vázquez, Josep A. Planell, Elisabeth Engel, Julia Buján, Natalio García-Honduvilla, María Vallet-Regí Published in: Acta Biomaterialia, Issue 45, 2016, Page(s) 349-356, ISSN 1742-7061 Publisher: Elsevier BV DOI: 10.1016/j.actbio.2016.09.016 Genetically Engineered Elastin-based Biomaterials for Biomedical Applications Author(s): Mercedes Santos, Sofia Serrano-Ducar, Juan Gonzalez-Valdivieso, Reinaldo Vallejo, Alessandra Girotti, Purificacion Cuadrado, Francisco Javier Arias Published in: Current Medicinal Chemistry, Issue 25, 2018, Page(s) 1-28, ISSN 0929-8673 Publisher: Bentham Science Publishers DOI: 10.2174/0929867325666180508094637 Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA Author(s): Hai Zemmour, David Planer, Judith Magenheim, Joshua Moss, Daniel Neiman, Dan Gilon, Amit Korach, Benjamin Glaser, Ruth Shemer, Giora Landesberg, Yuval Dor Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-018-03961-y Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease Author(s): Joshua Moss, Judith Magenheim, Daniel Neiman, Hai Zemmour, Netanel Loyfer, Amit Korach, Yaacov Samet, Myriam Maoz, Henrik Druid, Peter Arner, Keng-Yeh Fu, Endre Kiss, Kirsty L. Spalding, Giora Landesberg, Aviad Zick, Albert Grinshpun, A. M. James Shapiro, Markus Grompe, Avigail Dreazan Wittenberg, Benjamin Glaser, Ruth Shemer, Tommy Kaplan, Yuval Dor Published in: Nature Communications, Issue 9/1, 2018, Page(s) 1-12, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-018-07466-6 Self-assembly in Elastin-Like Recombinamers: a Mechanism to Mimic Natural Complexity Author(s): Luis Quintanilla-Sierra, Carmen García-Arévalo, J.C. Rodriguez-Cabello Published in: Materials Today Bio, 2019, Page(s) 100007, ISSN 2590-0064 Publisher: Elsevier DOI: 10.1016/j.mtbio.2019.100007 Monitoring liver damage using hepatocyte-specific methylation markers in cell-free circulating DNA Author(s): Roni Lehmann-Werman, Judith Magenheim, Joshua Moss, Daniel Neiman, Ofri Abraham, Sheina Piyanzin, Hai Zemmour, Ilana Fox, Talya Dor, Markus Grompe, Giora Landesberg, Bao-Li Loza, Abraham Shaked, Kim Olthoff, Benjamin Glaser, Ruth Shemer, Yuval Dor Published in: JCI Insight, Issue 3/12, 2018, ISSN 2379-3708 Publisher: JCI Insight DOI: 10.1172/jci.insight.120687 Hydrophobic Cholesteryl Moieties Trigger Substrate Cell–Membrane Interaction of Elastin–Mimetic Protein Coatings in Vitro Author(s): Leander Poocza, Filippo Cipriani, Matilde Alonso, José Carlos Rodríguez-Cabello Published in: ACS Omega, Issue 4/6, 2019, Page(s) 10818-10827, ISSN 2470-1343 Publisher: ACS Publications DOI: 10.1021/acsomega.9b00548 Use of proteolytic sequences with different cleavage kinetics as a way to generate hydrogels with preprogrammed cell-infiltration patterns imparted over their given 3D spatial structure Author(s): Tatjana Flora, I González de Torre, M Alonso, J Carlos Rodríguez-Cabello Published in: Biofabrication, Issue 11/3, 2019, Page(s) 035008, ISSN 1758-5090 Publisher: IOP Publishing DOI: 10.1088/1758-5090/ab10a5 Self-Assembling ELR-Based Nanoparticles as Smart Drug-Delivery Systems Modulating Cellular Growth via Akt Author(s): Juan Gonzalez-Valdivieso, Alessandra Girotti, Raquel Muñoz, J. Carlos Rodriguez-Cabello, F. Javier Arias Published in: Biomacromolecules, Issue 20/5, 2019, Page(s) 1996-2007, ISSN 1525-7797 Publisher: American Chemical Society DOI: 10.1021/acs.biomac.9b00206 Silk-ELR co-recombinamer covered stents obtained by electrospinning Author(s): M Putzu, F Causa, Manuel Parente, Israel González de Torre, J C Rodriguez-Cabello, P A Netti Published in: Regenerative Biomaterials, Issue 6/1, 2018, Page(s) 21-28, ISSN 2056-3418 Publisher: ACS Publications DOI: 10.1093/rb/rby022 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available