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New processes for the fermentative production of glycolipid biosurfactants and sialylated carbohydrates

New processes for the fermentative production of glycolipid biosurfactants and sialylated carbohydrates

Objective

This project aims to develop new processes and solve bottlenecks in the fermentative production of biosurfactants and specialty carbohydrates. Specifically, the project targets the development of innovative fermentation processes to produce the following compounds:
1. Glycolipid biosurfactants. The project targets four distinct classes of biosurfactants, specifically rhamnolipids, sophorolipids, xylolipids and mannosylerythritol-lipids with a wide range of application fields.
2. Specialty carbohydrates. Specifically, the project targets sialylated oligosaccharides, a class of very complex Human Milk Oligosaccharides that find application as a neutraceutical, pharmaceutical and cosmetic ingredient.

For both product lines, microbial producer strains will be developed through metabolic engineering. The fermentation process and down-stream processing will be developed and optimized in order to obtain an industrial process. Second generation technology based on lignocellulosic substrates will also be developed. Sufficient amounts of the new products will be produced for application testing, in order to evaluate their market potential in a wide range of application fields. The technical, economic, environmental and social sustainability of the process over the whole value chain from biomass to product application will also be assessed, with an emphasis on identifying and addressing the bottlenecks in the innovation chain. A valorisation plan will be drafted to complete the innovation process.

The project consortium has all the required players to obtain the expected impact: RTO's to address the research challenges in this project, an open innovation pilot plant to optimize and scale up the new processes, three biotech SMEs and three large industries to ensure the exploitation of the project results. In addition, two user groups (one for each product line) consisting of end-user companies are involved in the project.

Coordinator

UNIVERSITEIT GENT

Address

Sint Pietersnieuwstraat 25
9000 Gent

Belgium

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 707 767

Participants (11)

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BIO BASE EUROPE PILOT PLANT VZW

Belgium

EU Contribution

€ 951 750

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Germany

EU Contribution

€ 251 875

VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.

Belgium

EU Contribution

€ 252 500

IMD NATURAL SOLUTIONS GMBH

Germany

COMPAGNIE INDUSTRIELLE DE LA MATIERE VEGETAL CIM V

France

EVONIK INDUSTRIES AG

Germany

CRODA EUROPE LTD

United Kingdom

INBIOSE NV

Belgium

EU Contribution

€ 491 625

Carbosynth Limited

United Kingdom

EU Contribution

€ 75 088

EOC BELGIUM NV

Belgium

EVONIK NUTRITION & CARE GMBH

Germany

Project information

Grant agreement ID: 669003

Status

Closed project

  • Start date

    1 August 2015

  • End date

    31 July 2018

Funded under:

H2020-EU.3.2.6.

  • Overall budget:

    € 5 961 742,50

  • EU contribution

    € 2 730 605

Coordinated by:

UNIVERSITEIT GENT

Belgium