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New processes for the fermentative production of glycolipid biosurfactants and sialylated carbohydrates

Objective

This project aims to develop new processes and solve bottlenecks in the fermentative production of biosurfactants and specialty carbohydrates. Specifically, the project targets the development of innovative fermentation processes to produce the following compounds:
1. Glycolipid biosurfactants. The project targets four distinct classes of biosurfactants, specifically rhamnolipids, sophorolipids, xylolipids and mannosylerythritol-lipids with a wide range of application fields.
2. Specialty carbohydrates. Specifically, the project targets sialylated oligosaccharides, a class of very complex Human Milk Oligosaccharides that find application as a neutraceutical, pharmaceutical and cosmetic ingredient.

For both product lines, microbial producer strains will be developed through metabolic engineering. The fermentation process and down-stream processing will be developed and optimized in order to obtain an industrial process. Second generation technology based on lignocellulosic substrates will also be developed. Sufficient amounts of the new products will be produced for application testing, in order to evaluate their market potential in a wide range of application fields. The technical, economic, environmental and social sustainability of the process over the whole value chain from biomass to product application will also be assessed, with an emphasis on identifying and addressing the bottlenecks in the innovation chain. A valorisation plan will be drafted to complete the innovation process.

The project consortium has all the required players to obtain the expected impact: RTO's to address the research challenges in this project, an open innovation pilot plant to optimize and scale up the new processes, three biotech SMEs and three large industries to ensure the exploitation of the project results. In addition, two user groups (one for each product line) consisting of end-user companies are involved in the project.

Coordinator

UNIVERSITEIT GENT
Net EU contribution
€ 707 767,00
Address
Sint Pietersnieuwstraat 25
9000 Gent
Belgium

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Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Higher or Secondary Education Establishments
Other funding
€ 193 643,00

Participants (13)

BIO BASE EUROPE PILOT PLANT VZW
Belgium
Net EU contribution
€ 951 750,00
Address
Rodenhuizekaai 1
9042 Desteldonk Gent

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Other
Other funding
€ 0,00
FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany
Net EU contribution
€ 251 875,00
Address
Hansastrasse 27c
80686 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Other funding
€ 0,00
VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.
Belgium
Net EU contribution
€ 252 500,00
Address
Boeretang 200
2400 Mol

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Region
Vlaams Gewest Prov. Antwerpen Arr. Turnhout
Activity type
Research Organisations
Other funding
€ 0,00
IMD NATURAL SOLUTIONS GMBH
Germany
Net EU contribution
€ 0,00
Address
Otto Hahn Str 15
44227 Dortmund

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 569 062,50
COMPAGNIE INDUSTRIELLE DE LA MATIERE VEGETAL CIM V
France
Net EU contribution
€ 0,00
Address
14 Rue D'orleans
92573 Neuilly Sur Seine

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Hauts-de-Seine
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 512 812,50
EVONIK INDUSTRIES AG

Participation ended

Germany
Net EU contribution
€ 0,00
Address
Rellinghauser Strasse 1-11
45128 Essen
Region
Nordrhein-Westfalen Düsseldorf Essen, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 7 525,00
CRODA EUROPE LTD
United Kingdom
Net EU contribution
€ 0,00
Address
Cowick Hall Snaith
DN14 9AA Goole East Yorkshire

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Region
Yorkshire and the Humber East Yorkshire and Northern Lincolnshire East Riding of Yorkshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 647 500,00
INBIOSE
Belgium
Net EU contribution
€ 491 625,00
Address
Technologiepark 82 Bus 41
9052 Zwijnaarde

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 491 625,00
Carbosynth Limited
United Kingdom
Net EU contribution
€ 75 088,00
Address
Old Station Business Park 8 And 9
RG206NE Compton

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Berkshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 75 087,00
EOC BELGIUM NV
Belgium
Net EU contribution
€ 0,00
Address
Industriepark De Bruwaan 24
9700 Oudenaarde

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Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Oudenaarde
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 218 750,00
EVONIK OPERATIONS GMBH
Germany
Net EU contribution
€ 0,00
Address
Rellinghauser Strasse 1-11
45128 Essen

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Region
Nordrhein-Westfalen Düsseldorf Essen, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 474 411,50
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

EVONIK INDUSTRIES AG
Germany
Net EU contribution
€ 0,00
Address
Rellinghauser Strasse 1-11
45128 Essen

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Region
Nordrhein-Westfalen Düsseldorf Essen, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 8 557,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

EVONIK OPERATIONS GMBH
Germany
Net EU contribution
€ 0,00
Address
Rellinghauser Strasse 1-11
45128 Essen

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Region
Nordrhein-Westfalen Düsseldorf Essen, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 32 164,00