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New processes for the fermentative production of glycolipid biosurfactants and sialylated carbohydrates

Objective

This project aims to develop new processes and solve bottlenecks in the fermentative production of biosurfactants and specialty carbohydrates. Specifically, the project targets the development of innovative fermentation processes to produce the following compounds:
1. Glycolipid biosurfactants. The project targets four distinct classes of biosurfactants, specifically rhamnolipids, sophorolipids, xylolipids and mannosylerythritol-lipids with a wide range of application fields.
2. Specialty carbohydrates. Specifically, the project targets sialylated oligosaccharides, a class of very complex Human Milk Oligosaccharides that find application as a neutraceutical, pharmaceutical and cosmetic ingredient.

For both product lines, microbial producer strains will be developed through metabolic engineering. The fermentation process and down-stream processing will be developed and optimized in order to obtain an industrial process. Second generation technology based on lignocellulosic substrates will also be developed. Sufficient amounts of the new products will be produced for application testing, in order to evaluate their market potential in a wide range of application fields. The technical, economic, environmental and social sustainability of the process over the whole value chain from biomass to product application will also be assessed, with an emphasis on identifying and addressing the bottlenecks in the innovation chain. A valorisation plan will be drafted to complete the innovation process.

The project consortium has all the required players to obtain the expected impact: RTO's to address the research challenges in this project, an open innovation pilot plant to optimize and scale up the new processes, three biotech SMEs and three large industries to ensure the exploitation of the project results. In addition, two user groups (one for each product line) consisting of end-user companies are involved in the project.

Field of science

  • /engineering and technology/industrial biotechnology/bioprocessing technologies/fermentation
  • /natural sciences/biological sciences/synthetic biology
  • /social sciences/economics and business/economics/production economics
  • /social sciences/other social sciences/social sciences interdisciplinary/sustainable development
  • /natural sciences/biological sciences/biochemistry/biomolecules/carbohydrates
  • /engineering and technology/industrial biotechnology/metabolic engineering
  • /natural sciences/biological sciences/biochemistry/biomolecules/lipids
  • /social sciences/economics and business/business and management/commerce

Call for proposal

H2020-BBI-PPP-2014-1
See other projects for this call

Funding Scheme

BBI-RIA - Bio-based Industries Research and Innovation action

Coordinator

UNIVERSITEIT GENT
Address
Sint Pietersnieuwstraat 25
9000 Gent
Belgium
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 707 767

Participants (11)

BIO BASE EUROPE PILOT PLANT VZW
Belgium
EU contribution
€ 951 750
Address
Rodenhuizekaai 1
9042 Desteldonk Gent
Activity type
Other
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 251 875
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations
VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.
Belgium
EU contribution
€ 252 500
Address
Boeretang 200
2400 Mol
Activity type
Research Organisations
IMD NATURAL SOLUTIONS GMBH
Germany
EU contribution
€ 0
Address
Otto Hahn Str 15
44227 Dortmund
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
COMPAGNIE INDUSTRIELLE DE LA MATIERE VEGETAL CIM V
France
EU contribution
€ 0
Address
11 Bis Rue Louis Philippe
92200 Neuilly Sur Seine
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EVONIK INDUSTRIES AG

Participation ended

Germany
EU contribution
€ 0
Address
Rellinghauser Strasse 1-11
45128 Essen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CRODA EUROPE LTD
United Kingdom
EU contribution
€ 0
Address
Cowick Hall Snaith
DN14 9AA Goole East Yorkshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INBIOSE NV
Belgium
EU contribution
€ 491 625
Address
Technologiepark 3 Bus 41
9052 Gent
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Carbosynth Limited
United Kingdom
EU contribution
€ 75 088
Address
Old Station Business Park 8 And 9
RG206NE Compton
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EOC BELGIUM NV
Belgium
EU contribution
€ 0
Address
Industriepark De Bruwaan 24
9700 Oudenaarde
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EVONIK NUTRITION & CARE GMBH
Germany
EU contribution
€ 0
Address
Rellinghauser Strasse 1 11
45128 Essen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)