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European AIDS Vaccine Initiative 2020

Objective

HIV-1 is responsible for a global pandemic of 35 million people, and continues to spread at a rate of >2 million new infections/year. It is widely acknowledged that a protective vaccine would be the most effective means to reduce HIV-1 spread and ultimately eliminate the pandemic, while a therapeutic vaccine may help mitigate the clinical course of disease and lead to strategies of viral eradication. However despite 30 years of research, we do not have a vaccine capable of protecting from HIV-1 infection or impacting on disease progression. This in part represents the challenge of identifying immunogens and vaccine modalities with reduced risk of failure in late stage development. To overcome this bottleneck some of the most competitive research groups in vaccine discovery from European public institutions and biotechs from 9 EU countries together with top Australian and Canadian groups and US collaborators, have agreed to join forces in EAVI, providing a pool of international expertise at the highest level. EAVI2020 will provide a platform for the discovery and selection of several new, diverse and novel preventive and/or therapeutic vaccine candidates for HIV/AIDS. Emphasis will be placed on early rapid, iterative, small Experimental medicine (EM) human vaccine studies to select and refine the best immunogens, adjuvants, vectors, homologous and heterologous prime–boost schedules, and determine the impact of host factors such as gender and genetics. Animal models will be used to complement human studies, and to select novel immunization technologies to be advanced to the clinic. To shift the “risk curve” in product development we will develop innovative risk prediction methods, specifically designed to reduce the risk associated with late stage preventive or therapeutic vaccine failure, increasing the chance of discovery of an effective vaccine.

Call for proposal

H2020-PHC-2014-2015

See other projects for this call

Sub call

H2020-PHC-2015-single-stage_RTD

Coordinator

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Net EU contribution
€ 6 258 461,36
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
United Kingdom
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (26)

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Net EU contribution
€ 2 368 624,00
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 1 140 062,50
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
Spain
Net EU contribution
€ 1 998 031,25
Address
Carretera De Canyet
08916 Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ISTITUTO SUPERIORE DI SANITA
Italy
Net EU contribution
€ 389 700,00
Address
Viale Regina Elena 299
00161 Roma
Activity type
Research Organisations
Non-EU contribution
€ 0,00
POLYMUN SCIENTIFIC IMMUNBIOLOGISCHE FORSCHUNG GMBH
Austria
Net EU contribution
€ 3 519 158,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Donaustrasse 99
3400 Klosterneuburg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA

Participation ended

Spain
Net EU contribution
€ 421 119,29
Address
Carrer Rossello 149
08036 Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

HOSPITAL CLINIC DE BARCELONA

Participation ended

Spain
Net EU contribution
€ 16 888,86
Address
Calle Villarroel 170
08036 Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
Net EU contribution
€ 571 500,00
Address
Meibergdreef 15
1105AZ Amsterdam
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
France
Net EU contribution
€ 1 390 635,00
Address
Rue Leblanc 25
75015 Paris 15
Activity type
Research Organisations
Non-EU contribution
€ 0,00
OSPEDALE SAN RAFFAELE SRL
Italy
Net EU contribution
€ 669 938,75
Address
Via Olgettina 60
20132 Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSITE GRENOBLE ALPES
France
Net EU contribution
€ 612 907,50
Address
621 Avenue Centrale
38058 Grenoble
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Auvergne-Rhône-Alpes Rhône-Alpes Isère
 
KING'S COLLEGE LONDON
United Kingdom
Net EU contribution
€ 190 612,50
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
KAROLINSKA INSTITUTET
Sweden
Net EU contribution
€ 895 561,25
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 24 110,00
UNIVERSITATSKLINIKUM ERLANGEN
Germany
Net EU contribution
€ 564 021,00
Address
Maximiliansplatz 2
91054 Erlangen
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,25
Region
Bayern Mittelfranken Erlangen, Kreisfreie Stadt
THE UNIVERSITY OF WESTERN ONTARIO
Canada
Net EU contribution
€ 0,00
Address
Richmond Street Nord - Suite 2 1151
N6A 3K7 Ontario -London
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 386 600,00
NEMZETI ELELMISZERLANC-BIZTONSAGI HIVATAL
Hungary
Net EU contribution
€ 211 298,75
Address
Keleti Karoly Utca 24
1024 Budapest
Activity type
Other
Non-EU contribution
€ 0,00
LUDWIG BOLTZMANN GESELLSCHAFT GMBH

Participation ended

Austria
Net EU contribution
€ 201 250,00
Address
Nussdorfer Strasse 64 6 Stock
1090 Wien
Activity type
Research Organisations
Non-EU contribution
€ 0,00
BIONTECH RNA PHARMACEUTICALS GMBH

Participation ended

Germany
Net EU contribution
€ 92 902,55
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
An Der Goldgrube 12
55131 Mainz
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Rheinland-Pfalz Rheinhessen-Pfalz Mainz, Kreisfreie Stadt
 
INSTITUTO DE SALUD CARLOS III
Spain
Net EU contribution
€ 403 828,75
Address
Monforte De Lemos 5
28029 Madrid
Activity type
Research Organisations
Non-EU contribution
€ 500,00
STICHTING INTERNATIONAL AIDS VACCINE INITIATIVE THE NETHERLANDS

Participation ended

Netherlands
Net EU contribution
€ 0,00
Address
Van Diemenstraat 20, 200 Unit 48
1013 NH Amsterdam
Activity type
Other
Non-EU contribution
€ 0,00
Region
West-Nederland Noord-Holland Groot-Amsterdam
 
UNIVERSITY OF MELBOURNE
Australia
Net EU contribution
€ 0,00
Address
Parkvilleoffice Of The Vice Chancellor
3010 Melbourne
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 514 641,25
UNIVERSITY OF NEW SOUTH WALES
Australia
Net EU contribution
€ 0,00
Address
Anzac Parade
2052 Sydney
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 214 891,25
GENOME RESEARCH LIMITED

Participation ended

United Kingdom
Net EU contribution
€ 0,00
Address
The Gibbs Building, Euston Road 215
NW1 2BE London
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Region
London Inner London — West Camden and City of London
INTERNATIONAL AIDS VACCINE INITIATIVE INC
United States
Net EU contribution
€ 626 000,00
Address
125 Broad Street, 9Th Floor
10004 New York
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITY OF SOUTHAMPTON
United Kingdom
Net EU contribution
€ 210 343,75
Address
Highfield
SO17 1BJ Southampton
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
South East (England) Hampshire and Isle of Wight Southampton
FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA
Spain
Net EU contribution
€ 195 177,19
Address
Passeig Vall D Hebron 119-129 Edificio De Recerca
08035 Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,00